Literature DB >> 22579244

Mutual remodeling and conformation grid: a mediator code?

Peter A Meyer1, Jianhua Fu.   

Abstract

How does a common RNA polymerase II apparatus generate a complex pattern of transcripts in response to many gene-specific transcription factors and in accordance with cell's state? In this issue of Structure, Cai et al. reveal that the process involves coordinated conformational changes in Pol II and Mediator.
Copyright © 2012 Elsevier Ltd. All rights reserved.

Entities:  

Year:  2012        PMID： 22579244      PMCID： PMC3351759          DOI： 10.1016/j.str.2012.04.008

Source DB:  PubMed          Journal:  Structure        ISSN： 0969-2126            Impact factor:   5.006


  12 in total

Review 1.  Elongation by RNA polymerase II: structure-function relationship.

Authors:  Averell Gnatt
Journal:  Biochim Biophys Acta       Date:  2002-09-13

Review 2.  The human Mediator complex: a versatile, genome-wide regulator of transcription.

Authors:  Dylan J Taatjes
Journal:  Trends Biochem Sci       Date:  2010-03-17       Impact factor: 13.807

Review 3.  Mediator and the mechanism of transcriptional activation.

Authors:  Roger D Kornberg
Journal:  Trends Biochem Sci       Date:  2005-05       Impact factor: 13.807

4.  Mediator comes out from the shadows.

Authors:  Ronald C Conaway; Joan Weliky Conaway
Journal:  Structure       Date:  2009-04-15       Impact factor: 5.006

Review 5.  Gene-specific transcription activation via long-range allosteric shape-shifting.

Authors:  Chung-Jung Tsai; Ruth Nussinov
Journal:  Biochem J       Date:  2011-10-01       Impact factor: 3.857

6.  Architecture of the Mediator head module.

Authors:  Tsuyoshi Imasaki; Guillermo Calero; Gang Cai; Kuang-Lei Tsai; Kentaro Yamada; Francesco Cardelli; Hediye Erdjument-Bromage; Paul Tempst; Imre Berger; Guy Lorch Kornberg; Francisco J Asturias; Roger D Kornberg; Yuichiro Takagi
Journal:  Nature       Date:  2011-07-03       Impact factor: 49.962

7.  Yeast RNA polymerase II at 5 A resolution.

Authors:  J Fu; A L Gnatt; D A Bushnell; G J Jensen; N E Thompson; R R Burgess; P R David; R D Kornberg
Journal:  Cell       Date:  1999-09-17       Impact factor: 41.582

8.  Mediator head module structure and functional interactions.

Authors:  Gang Cai; Tsuyoshi Imasaki; Kentaro Yamada; Francesco Cardelli; Yuichiro Takagi; Francisco J Asturias
Journal:  Nat Struct Mol Biol       Date:  2010-02-14       Impact factor: 15.369

9.  Molecular architecture and conformational flexibility of human RNA polymerase II.

Authors:  Seth A Kostek; Patricia Grob; Sacha De Carlo; J Slaton Lipscomb; Florian Garczarek; Eva Nogales
Journal:  Structure       Date:  2006-11       Impact factor: 5.006

10.  Malleable machines in transcription regulation: the mediator complex.

Authors:  Agnes Tóth-Petróczy; Christopher J Oldfield; István Simon; Yuichiro Takagi; A Keith Dunker; Vladimir N Uversky; Monika Fuxreiter
Journal:  PLoS Comput Biol       Date:  2008-12-19       Impact factor: 4.475
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  2 in total

Review 1.  The Spt4-Spt5 complex: a multi-faceted regulator of transcription elongation.

Authors:  Grant A Hartzog; Jianhua Fu
Journal:  Biochim Biophys Acta       Date:  2012-09-06

2.  The head module of Mediator directs activation of preloaded RNAPII in vivo.

Authors:  Sarah K Lee; Xu Chen; Liangqun Huang; Laurie A Stargell
Journal:  Nucleic Acids Res       Date:  2013-09-04       Impact factor: 16.971
  2 in total

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