Literature DB >> 2257852

Assay detection limits: concept, definition, and estimation.

A B Nix1, D W Wilson.   

Abstract

This paper emphasizes the need for standardizing the definition and estimation of the minimum detectable analyte concentration in an assay. It reviews the key papers that are most frequently quoted in the literature to illustrate the variety of procedures currently in use.

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Year:  1990        PMID: 2257852     DOI: 10.1007/bf00315096

Source DB:  PubMed          Journal:  Eur J Clin Pharmacol        ISSN: 0031-6970            Impact factor:   2.953


  1 in total

1.  Statistical estimation of the minimal detectable concentration ("sensitivity") for radioligand assays.

Authors:  D Rodbard
Journal:  Anal Biochem       Date:  1978-10-01       Impact factor: 3.365

  1 in total
  2 in total

1.  Use of pharmacokinetic data below lower limit of quantitation values.

Authors:  William J Jusko
Journal:  Pharm Res       Date:  2012-06-23       Impact factor: 4.200

2.  Evaluation of pharmacokinetic studies: is it useful to take into account concentrations below the limit of quantification?

Authors:  H Humbert; M D Cabiac; J Barradas; C Gerbeau
Journal:  Pharm Res       Date:  1996-06       Impact factor: 4.200

  2 in total

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