Literature DB >> 22577266

Efficacy and safety of 1,064 nm Q-switched Nd:YAG laser treatment for removing melanocytic nevi.

Yoon Jee Kim1, Kyu Uang Whang, Won Bok Choi, Hyun Jo Kim, Jae Young Hwang, Jung Hoon Lee, Sung Wook Kim.   

Abstract

BACKGROUND: Until recently, the removal of melanocytic nevi has been performed with a CO(2) laser or Er:YAG laser. These lasers have been useful for removing affected spots. However, enlargement of spots or some sequelae, including depressed or hypertrophic scars, could develop as unwanted results. The Q-switched Nd:YAG laser has been used to remove deep-seated melanocytes, such as Ota nevus or tattoos. However, there have been no previous experiments performed to test the efficacy and safety of this laser treatment for melanocytic nevi.
OBJECTIVE: The objective of this study was to investigate the efficacy and safety of the 1,064 nm Q-switched Nd:YAG laser for removing melanocytic nevi, including congenital nevomelanocytic and acquired nevomelanocytic nevi.
METHODS: Two thousand and sixty four Korean patients with small melanocytic nevi were treated with a Q-switched Nd:YAG laser from 2005 to 2009. High-resolution photographs were taken in identical lighting and positions before and after the six weeks of treatment to observe the procedural efficacy.
RESULTS: About 70% of the nevi treated using a 1,064 nm Q-switched Nd:YAG laser were completely removed after one session. The other 30% were completely treated within three sessions. The appearance of sequelae such as hollow scars noticeably decreased compared to the results seen in CO(2) or Er:YAG laser treatments.
CONCLUSION: Use of the 1,064 nm Q-switched Nd:YAG laser is a safe and effective treatment modality for melanocytic nevi.

Entities:  

Keywords:  Melanocytic nevi; Nevi; Q-switched Nd:YAG

Year:  2012        PMID: 22577266      PMCID: PMC3346906          DOI: 10.5021/ad.2012.24.2.162

Source DB:  PubMed          Journal:  Ann Dermatol        ISSN: 1013-9087            Impact factor:   1.444


  11 in total

1.  Laser treatment of pigmented lesions--2000: how far have we gone?

Authors:  A J Stratigos; J S Dover; K A Arndt
Journal:  Arch Dermatol       Date:  2000-07

2.  Changes of biophysical properties of the skin measured by non-invasive techniques after Q-switched Nd-YAG laser therapy in patients with nevus of Ota.

Authors:  S D Kim; S W Kim; C H Huh; D H Suh; H C Eun
Journal:  Skin Res Technol       Date:  2001-11       Impact factor: 2.365

Review 3.  Clinical application of lasers in Asians.

Authors:  Henry H Chan; Murad Alam; Taro Kono; Jeffery S Dover
Journal:  Dermatol Surg       Date:  2002-07       Impact factor: 3.398

4.  Treatment of post-inflammatory hyperpigmentation using 1064-nm Q-switched Nd:YAG laser with low fluence: report of three cases.

Authors:  S B Cho; S J Park; J S Kim; M J Kim; T S Bu
Journal:  J Eur Acad Dermatol Venereol       Date:  2009-04-23       Impact factor: 6.166

5.  Comparison of the Q-switched alexandrite (755 nm) and Q-switched Nd:YAG (1064 nm) lasers in the treatment of benign melanocytic nevi.

Authors:  A Rosenbach; C M Williams; T S Alster
Journal:  Dermatol Surg       Date:  1997-04       Impact factor: 3.398

6.  Selective photothermolysis: precise microsurgery by selective absorption of pulsed radiation.

Authors:  R R Anderson; J A Parrish
Journal:  Science       Date:  1983-04-29       Impact factor: 47.728

7.  An in vivo trial comparing the clinical efficacy and complications of Q-switched 755 nm alexandrite and Q-switched 1064 nm Nd:YAG lasers in the treatment of nevus of Ota.

Authors:  H H Chan; S Y Ying; W S Ho; T Kono; W W King
Journal:  Dermatol Surg       Date:  2000-10       Impact factor: 3.398

8.  Treatment of Hori's nevus with the Q-switched Nd:YAG laser.

Authors:  N Polnikorn; S Tanrattanakorn; D J Goldberg
Journal:  Dermatol Surg       Date:  2000-05       Impact factor: 3.398

9.  Treatment of acquired bilateral nevus of Ota-like macules (Hori's nevus) using 1064-nm Q-switched Nd:YAG laser with low fluence.

Authors:  Sung Bin Cho; Soo Jie Park; Moon Jung Kim; Tae Sung Bu
Journal:  Int J Dermatol       Date:  2009-12       Impact factor: 2.736

10.  Selective photothermolysis of cutaneous pigmentation by Q-switched Nd: YAG laser pulses at 1064, 532, and 355 nm.

Authors:  R R Anderson; R J Margolis; S Watenabe; T Flotte; G J Hruza; J S Dover
Journal:  J Invest Dermatol       Date:  1989-07       Impact factor: 8.551

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  7 in total

1.  Treatment of Congenital Melanocytic Nevi With a Dual-Wavelengths Copper Vapor Laser: A Case Series.

Authors:  Igor V Ponomarev; Sergey B Topchiy; Alexandra E Pushkareva; Svetlana V Klyuchareva; Yury N Andrusenko
Journal:  J Lasers Med Sci       Date:  2021-02-14

Review 2.  Lasers for nevi: a review.

Authors:  Harleen Arora; Leyre Falto-Aizpurua; Anna Chacon; Robert D Griffith; Keyvan Nouri
Journal:  Lasers Med Sci       Date:  2014-12-16       Impact factor: 3.161

3.  Evaluation of Efficacy and Safety of Low-Fluence Q-Switched 1064-nm Laser in Infra-orbital Hyperpigmentation Based on Biometric Parameters.

Authors:  Shiva Alavi; Azadeh Goodarzi; Mohammad Ali Nilforoushzadeh; Parvin Mansouri; Mohammad Amin Jafari; Somayeh Hejazi; Zahra Azizian
Journal:  J Lasers Med Sci       Date:  2022-04-12

4.  Laser treatment of congenital melanocytic nevi: a review of the literature.

Authors:  Fleta N Bray; Vidhi Shah; Keyvan Nouri
Journal:  Lasers Med Sci       Date:  2015-11-12       Impact factor: 3.161

Review 5.  Optimal management of common acquired melanocytic nevi (moles): current perspectives.

Authors:  Kabir Sardana; Payal Chakravarty; Khushbu Goel
Journal:  Clin Cosmet Investig Dermatol       Date:  2014-03-19

6.  Final congenital melanocytic naevi colour is determined by normal skin colour and unaltered by superficial removal techniques: a longitudinal study.

Authors:  S Polubothu; V A Kinsler
Journal:  Br J Dermatol       Date:  2019-08-07       Impact factor: 9.302

7.  Single Treatment with 100-Microsecond Alexandrite Laser Clears Selected Acquired Melanocytic Nevi in Type IV Asian Facial Skin.

Authors:  Etienne Ce Wang; Priya Sen; Chee-Leok Goh; Sze-Hon Chua
Journal:  J Cutan Aesthet Surg       Date:  2013-01
  7 in total

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