Literature DB >> 22577182

Validity of self-reported prevalent cases of stroke and acute myocardial infarction in the Spanish cohort of the EPIC study.

Monica Machón1, Larraitz Arriola, Nerea Larrañaga, Pilar Amiano, Concepción Moreno-Iribas, Antonio Agudo, Eva Ardanaz, Aurelio Barricarte, Genevieve Buckland, Ma Dolores Chirlaque, Diana Gavrila, José María Huerta, Carmen Martínez, Esther Molina, Carmen Navarro, José Ramón Quiros, Laudina Rodríguez, María José Sanchez, Carlos Alberto González, Miren Dorronsoro.   

Abstract

BACKGROUND: Information on the validity of self-reported cases of stroke and acute myocardial infarction (AMI) is varied. The aim of this study was to assess the validity and agreement of self-reported prevalent cases of stroke and AMI in the Spanish cohort of the European Prospective Investigation into Cancer and Nutrition (EPIC).
METHODS: At recruitment, 1992-1996, and in the follow-up (3 years after recruitment), each participant in the Spanish EPIC cohort (15,630 men and 25,808 women) was asked if a doctor had ever said that they had had a stroke or AMI, and the results were compared with information available in medical records. Validity of self-reported prevalent cases of stroke and AMI was examined by calculating sensitivity, specificity, positive predictive values and κ statistics.
RESULTS: The sensitivity of self-reported prevalent cases of stroke was 81.3% and that for AMI was 97.7%. The positive predictive value was 22.2% and 60.7% for stroke and AMI, respectively, whereas specificity was very high (>99%) for both diseases. The agreement between self-report questionnaire results and medical records was substantial (κ=0.75) for AMI but not for stroke (κ=0.35).
CONCLUSION: Self-reported information on stroke and AMI included in the EPIC questionnaire is a valid instrument for the assessment of AMI disease but should be used with caution in stroke.

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Year:  2012        PMID: 22577182     DOI: 10.1136/jech-2011-200104

Source DB:  PubMed          Journal:  J Epidemiol Community Health        ISSN: 0143-005X            Impact factor:   3.710


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