Literature DB >> 22576421

Adherence to guidelines and its impact on outcomes in patients hospitalized with community-acquired pneumonia at a university hospital.

Carla Discacciati Silveira1, Cid Sérgio Ferreira, Ricardo de Amorim Corrêa.   

Abstract

OBJECTIVE: To evaluate the agreement between the criteria used for hospitalization of patients with community-acquired pneumonia (CAP) and those of the Brazilian Thoracic Association guidelines, and to evaluate the association of that agreement with 30-day mortality. Secondarily, to evaluate the agreement between the treatment given and that recommended in the guidelines with length of hospital stay, microbiological profile, 12-month mortality, complications, ICU admission, mechanical ventilation, and 30-day mortality.
METHODS: This was a retrospective study involving adult patients hospitalized between 2005 and 2007 at the Federal University of Minas Gerais Hospital das Clínicas, located in Belo Horizonte, Brazil. Medical charts and chest X-rays were reviewed.
RESULTS: Among the 112 patients included in the study, admission and treatment criteria were in accordance with the guidelines in 82 (73.2%) and 66 (58.9%), respectively. The 30-day and 12-month mortality rates were 12.3% and 19.4%, respectively. The 30-day mortality rate was lower for patients in whom the CRB-65 (mental Confusion, Respiratory rate, Blood pressure, and age > 65 years) score was 1-2 and the antibiotic therapy was in accordance with the guidelines (p = 0.01). Cerebrovascular disease and appropriate antibiotic therapy showed independent associations with 30-day mortality. There was a trend toward an association between guideline-concordant antibiotic therapy and shorter hospital stay.
CONCLUSIONS: In the population studied, admission and treatment criteria that were in accordance with the guidelines were associated with favorable outcomes in hospitalized patients with CAP. Cerebrovascular disease, as a risk factor, and guideline-concordant antibiotic therapy, as a protective factor, were associated with 30-day mortality.

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Year:  2012        PMID: 22576421     DOI: 10.1590/s1806-37132012000200002

Source DB:  PubMed          Journal:  J Bras Pneumol        ISSN: 1806-3713            Impact factor:   2.624


  5 in total

1.  Impact of Guideline Adherence on Outcomes in Patients Hospitalized with Community-Acquired Pneumonia (CAP) in Hungary: A Retrospective Observational Study.

Authors:  Adina Fésüs; Ria Benkő; Mária Matuz; Zsófia Engi; Roxána Ruzsa; Helga Hambalek; Árpád Illés; Gábor Kardos
Journal:  Antibiotics (Basel)       Date:  2022-03-30

2.  Management of severe community-acquired pneumonia in Brazil: a secondary analysis of an international survey.

Authors:  Lígia Rabello; Catarina Conceição; Katia Ebecken; Thiago Lisboa; Fernando Augusto Bozza; Márcio Soares; Pedro Póvoa; Jorge Ibrain Figueira Salluh
Journal:  Rev Bras Ter Intensiva       Date:  2015-03-01

3.  Community-acquired pneumonia: economics of inpatient medical care vis-à-vis clinical severity.

Authors:  Vojislav Cupurdija; Zorica Lazic; Marina Petrovic; Slavica Mojsilovic; Ivan Cekerevac; Nemanja Rancic; Mihajlo Jakovljevic
Journal:  J Bras Pneumol       Date:  2015 Jan-Feb       Impact factor: 2.624

4.  Clinical, epidemiological, and etiological profile of inpatients with community-acquired pneumonia in a public hospital in the interior of Brazil.

Authors:  Laura Fuchs Bahlis; Luciano Passamani Diogo; Ricardo de Souza Kuchenbecker; Sandra Costa Fuchs
Journal:  J Bras Pneumol       Date:  2018 Jul-Aug       Impact factor: 2.624

5.  Community-acquired pneumonia: challenges of the situation in Brazil.

Authors:  Mauro Gomes
Journal:  J Bras Pneumol       Date:  2018 Jul-Aug       Impact factor: 2.624

  5 in total

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