Literature DB >> 22575556

[Prevalence of chronic renal insufficiency in diabetic type 2 diabetes patients based on the estimated glomerular filtration rate and relation with cardiovascular risk].

Teresa Mur Martí1, Mercè Villaró Gabarrós, Nuria Porta Martínez, Angels Jaén Manzanera.   

Abstract

BACKGROUND AND
OBJECTIVE: The aim of this study was: to estimate the prevalence of chronic renal insufficiency (CRI) in diabetic type 2 (DM2) patients treated in Primary Care based on the estimated glomerular filtration rate (GFe); to determine associated factors with CRI, and to evaluate the relationship of GF rate and risk of cardiovascular disease. PATIENTS AND METHODS: This was a descriptive cross-sectional study. We included 500 medical histories randomly selected in a total of 2,950 DM2 patients. We registered sociodemographic data, comorbidities, cardiovascular risk factors and laboratory data. CRI definition was based on GFe rate and classified according to the K/DOQI Clinical Practice Guidelines for Chronic Kidney Disease.
RESULTS: The prevalence of CRI was 23.2%. There were 51.6% females and the mean age was 66.2 years; 70,4% had hypertension and 67% dyslipidemia. The presence of CRI was related with older age, females, smoking habit, plasma creatinine value, microalbuminuria, and history of hypertension, dyslipidemia and cardiovascular disease. After analysing the data according to the category of GF rate, only the significant relationship with smoking habit disappeared. Multivariate statistic analysis supports a relation with older age, female gender, dyslipidemia and heart disease.
CONCLUSIONS: We confirm a high prevalence of CRI in DM2 patients and their relationship with the presence of cardiovascular disease.
Copyright © 2011 Elsevier España, S.L. All rights reserved.

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Year:  2012        PMID: 22575556     DOI: 10.1016/j.medcli.2012.03.011

Source DB:  PubMed          Journal:  Med Clin (Barc)        ISSN: 0025-7753            Impact factor:   1.725


  2 in total

1.  Relationship Between Hematocrit Level and Cardiovascular Risk Factors in a Community-Based Population.

Authors:  Yuan-Ze Jin; Dong-Han Zheng; Zhi-Ying Duan; Ying-Zi Lin; Xue-Ying Zhang; Jing-Ru Wang; Shuo Han; Guo-Feng Wang; Yi-Jing Zhang
Journal:  J Clin Lab Anal       Date:  2014-05-21       Impact factor: 2.352

2.  Combined effects of admission serum creatinine concentration with age and gender on the prognostic significance of subjects with acute ST-elevation myocardial infarction in China.

Authors:  Zhao-Yang Li; Zhao-Hong Chen; Feng-Hui An; Li-Hua Li; Chang-Yan Guo; Yan Gu; Zhe Liu; Tie-Bing Zhu; Lian-Sheng Wang; Chun-Jian Li; Xiang-Qing Kong; Wen-Zhu Ma; Zhi-Jian Yang; En-Zhi Jia
Journal:  PLoS One       Date:  2014-10-10       Impact factor: 3.240

  2 in total

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