| Literature DB >> 22575500 |
Yuri G Anissimov1, Owen G Jepps, Yuri Dancik, Michael S Roberts.
Abstract
Topical delivery to the various regions of the skin and underlying tissues, transdermal drug delivery and dermal exposure to environmental chemicals are important areas of research. Mathematical models of epidermal and dermal transport, involving penetration of a solute through various layers of the skin, metabolism in the skin and its subsequent distribution and clearance into systemic circulation from underlying tissues, play an essential role in this research area and are reviewed in this work.Mesh：
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Year: 2012 PMID： 22575500 DOI： 10.1016/j.addr.2012.04.009
Source DB: PubMed Journal: Adv Drug Deliv Rev ISSN： 0169-409X Impact factor: 15.470