Literature DB >> 22573031

Cu(II)-catalyzed C-H (SP3) oxidation and C-N cleavage: base-switched methylenation and formylation using tetramethylethylenediamine as a carbon source.

Lei Zhang1, Chen Peng, Dan Zhao, Yue Wang, Hai-Jian Fu, Qi Shen, Jian-Xin Li.   

Abstract

Base-switched methylenation and formylation using tetramethylethylenediamine (TMEDA) as a carbon source have been achieved under mild conditions, catalyzed by CuCl(2), with atmospheric oxygen as oxidant. Bisindolylmethanes, diphenylmethanes and 3-formylindoles were synthesized with excellent regioselectivity and good yield.

Entities:  

Year:  2012        PMID： 22573031     DOI： 10.1039/c2cc32009f

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  2 in total

1.  Electrosynthesis of Quinazolines and Quinazolinones via an Anodic Direct Oxidation C(sp3)-H Amination/C-N Cleavage of Tertiary Amine in Aqueous Medium.

Authors:  Zhenghong Zhou; Kangfei Hu; Jiawei Wang; Zhibin Li; Yan Zhang; Zhenggen Zha; Zhiyong Wang
Journal:  ACS Omega       Date:  2020-12-01

2.  Metal-free oxidative coupling of arylmethylamines with indoles: a simple, environmentally benign approach for the synthesis of 3,3'-bis(indolyl)methanes.

Authors:  Vikas D Kadu; Sankala Naga Chandrudu; Mahesh G Hublikar; Dattatraya G Raut; Raghunath B Bhosale
Journal:  RSC Adv       Date:  2020-06-17       Impact factor: 4.036
  2 in total

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