Literature DB >> 22571611

The emerging role of CXC chemokines and their receptors in cancer.

Victoria Vinader1, Kamyar Afarinkia.   

Abstract

Chemokines and their receptors have a multifaceted role in tumor biology and are implicated in nearly all aspects of cancer growth, survival and dissemination. Modulation of the interaction between chemokines and their cell surface receptor is, therefore, a promising area for the development of new cancer medicines. In this review, we look at the compelling evidence that is emerging to support targeting CXC chemokines, also known as family α chemokines, as novel therapeutic strategies in the treatment of cancer.

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Year:  2012        PMID： 22571611     DOI： 10.4155/fmc.12.48

Source DB:  PubMed          Journal:  Future Med Chem        ISSN： 1756-8919            Impact factor:   3.808


  14 in total

1.  Inflammatory microenvironment and expression of chemokines in hepatocellular carcinoma.

Authors:  Ke-Qi Han; Xue-Qun He; Meng-Yu Ma; Xiao-Dong Guo; Xue-Min Zhang; Jie Chen; Hui Han; Wei-Wei Zhang; Quan-Gang Zhu; Hua Nian; Li-Jun Ma
Journal:  World J Gastroenterol       Date:  2015-04-28       Impact factor: 5.742

2.  The PNPLA3 I148M variant promotes lipid-induced hepatocyte secretion of CXC chemokines establishing a tumorigenic milieu.

Authors:  Hans Dieter Nischalke; Philipp Lutz; Eva Bartok; Benjamin Krämer; Bettina Langhans; Regina Frizler; Thomas Berg; Jochen Hampe; Stephan Buch; Christian Datz; Felix Stickel; Gunther Hartmann; Christian P Strassburg; Jacob Nattermann; Ulrich Spengler
Journal:  J Mol Med (Berl)       Date:  2019-10-21       Impact factor: 4.599

3.  The Ovarian Cancer Chemokine Landscape Is Conducive to Homing of Vaccine-Primed and CD3/CD28-Costimulated T Cells Prepared for Adoptive Therapy.

Authors:  Emese Zsiros; Priyanka Duttagupta; Denarda Dangaj; Hongzhe Li; Renee Frank; Thomas Garrabrant; Ian S Hagemann; Bruce L Levine; Carl H June; Lin Zhang; Ena Wang; Francesco M Marincola; Davide Bedognetti; Daniel J Powell; Janos Tanyi; Michael D Feldman; Lana E Kandalaft; George Coukos
Journal:  Clin Cancer Res       Date:  2015-02-23       Impact factor: 12.531

Review 4.  The role of chemokines in Guillain-Barré syndrome.

Authors:  Sharon Chiang; Eroboghene E Ubogu
Journal:  Muscle Nerve       Date:  2013-07-27       Impact factor: 3.217

Review 5.  Big opportunities for small molecules in immuno-oncology.

Authors:  Jerry L Adams; James Smothers; Roopa Srinivasan; Axel Hoos
Journal:  Nat Rev Drug Discov       Date:  2015-07-31       Impact factor: 84.694

6.  Fibroblast activation protein α-positive pancreatic stellate cells promote the migration and invasion of pancreatic cancer by CXCL1-mediated Akt phosphorylation.

Authors:  Zhang Wen; Qiaofei Liu; Jihua Wu; Banghao Xu; Jilong Wang; Lizhou Liang; Ya Guo; Minhao Peng; Yupei Zhao; Quan Liao
Journal:  Ann Transl Med       Date:  2019-10

Review 7.  A meta-analysis for CXCR4 as a prognostic marker and potential drug target in non-small cell lung cancer.

Authors:  Changyuan Zhang; Jie Li; Yi Han; Jian Jiang
Journal:  Drug Des Devel Ther       Date:  2015-06-24       Impact factor: 4.162

8.  Clinicopathological significance of CXCR4 in non-small cell lung cancer.

Authors:  Xiao-Ming Zhou; Lan He; Gang Hou; Bing Jiang; Yuan-He Wang; Li Zhao
Journal:  Drug Des Devel Ther       Date:  2015-03-05       Impact factor: 4.162

9.  Roles of CXCL5 on migration and invasion of liver cancer cells.

Authors:  Xiaojing Xu; Peixin Huang; Biwei Yang; Xiangdong Wang; Jinglin Xia
Journal:  J Transl Med       Date:  2014-07-10       Impact factor: 5.531

10.  Chemokine CXCL1 may serve as a potential molecular target for hepatocellular carcinoma.

Authors:  Ke-Qi Han; Hui Han; Xue-Qun He; Lei Wang; Xiao-Dong Guo; Xue-Ming Zhang; Jie Chen; Quan-Gang Zhu; Hua Nian; Xiao-Feng Zhai; Ma-Wei Jiang
Journal:  Cancer Med       Date:  2016-09-28       Impact factor: 4.452
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