Literature DB >> 22570645

Targeting Mitochondria by Olesoxime or Complement 1q Binding Protein as a Novel Management for Autism: A Hypothesis.

A Ghanizadeh1.   

Abstract

Excitotoxicity, oxidative stress, and mitochondrial dysfunction are associated with autism. Considering the preventive role of complement 1q binding protein or olesoxime for the opening of mitochondrial permeability transition pore mediated by oxidative stress, it is hypothesized that complement 1q binding protein or olesoxime may improve some symptoms of autism.

Entities:  

Year:  2011        PMID： 22570645      PMCID： PMC3343746          DOI： 10.1159/000332202

Source DB:  PubMed          Journal:  Mol Syndromol        ISSN： 1661-8769


  22 in total

1.  Oxidative stress may mediate association of stereotypy and immunity in autism, a novel explanation with clinical and research implications.

Authors:  Ahmad Ghanizadeh
Journal:  J Neuroimmunol       Date:  2010-11-13       Impact factor: 3.478

2.  Methionine sulfoximine may improve inflammation in autism, a novel hypothesized treatment for autism.

Authors:  Ahmad Ghanizadeh
Journal:  Arch Med Res       Date:  2010-11       Impact factor: 2.235

Review 3.  Modeling autistic features in animals.

Authors:  Paul H Patterson
Journal:  Pediatr Res       Date:  2011-05       Impact factor: 3.756

4.  Nuclear factor kappa B may increase insight into the management of neuroinflammation and excitotoxicity in autism.

Authors:  Ahmad Ghanizadeh
Journal:  Expert Opin Ther Targets       Date:  2011-05-10       Impact factor: 6.902

5.  Rett syndrome microglia damage dendrites and synapses by the elevated release of glutamate.

Authors:  Izumi Maezawa; Lee-Way Jin
Journal:  J Neurosci       Date:  2010-04-14       Impact factor: 6.167

6.  Evaluation of oxidative stress in autism: defective antioxidant enzymes and increased lipid peroxidation.

Authors:  Nagwa A Meguid; Ahmed A Dardir; Ehab R Abdel-Raouf; Adel Hashish
Journal:  Biol Trace Elem Res       Date:  2010-09-16       Impact factor: 3.738

7.  Complement 1q-binding protein inhibits the mitochondrial permeability transition pore and protects against oxidative stress-induced death.

Authors:  Allison M McGee; Christopher P Baines
Journal:  Biochem J       Date:  2011-01-01       Impact factor: 3.857

8.  High nitric oxide production in autistic disorder: a possible role for interferon-gamma.

Authors:  Thayne L Sweeten; David J Posey; Sudha Shankar; Christopher J McDougle
Journal:  Biol Psychiatry       Date:  2004-02-15       Impact factor: 13.382

9.  Reduction of striatal N-methyl-D-aspartate toxicity by inhibition of nitric oxide synthase.

Authors:  H Kollegger; G J McBean; K F Tipton
Journal:  Biochem Pharmacol       Date:  1993-01-07       Impact factor: 5.858

10.  Cellular and mitochondrial glutathione redox imbalance in lymphoblastoid cells derived from children with autism.

Authors:  S Jill James; Shannon Rose; Stepan Melnyk; Stefanie Jernigan; Sarah Blossom; Oleksandra Pavliv; David W Gaylor
Journal:  FASEB J       Date:  2009-03-23       Impact factor: 5.191
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  3 in total

1.  A randomized double blind placebo controlled clinical trial of N-Acetylcysteine added to risperidone for treating autistic disorders.

Authors:  Ahmad Ghanizadeh; Ebrahim Moghimi-Sarani
Journal:  BMC Psychiatry       Date:  2013-07-25       Impact factor: 3.630

2.  LIGAND-RECEPTOR INTERACTIONS AND DRUG DESIGN.

Authors:  Yanling Zhang; Jianrui Song; Xiaojun Zhang; Yuanyuan Xiao
Journal:  Biochem Insights       Date:  2015-12-20

3.  Physical exercise and intermittent administration of lactulose may improve autism symptoms through hydrogen production.

Authors:  Ahmad Ghanizadeh
Journal:  Med Gas Res       Date:  2012-07-30
  3 in total

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