Literature DB >> 22569263

UGT75L6 and UGT94E5 mediate sequential glucosylation of crocetin to crocin in Gardenia jasminoides.

Mai Nagatoshi1, Kazuyoshi Terasaka, Miki Owaki, Makiko Sota, Tatsunori Inukai, Akito Nagatsu, Hajime Mizukami.   

Abstract

Crocin is an apocarotenoid glycosyl ester accumulating in fruits of Gardenia jasminoides and used as a food coloring and nutraceutical. For the first time, the two glucosyltransferases UGT75L6 and UGT94E5 that sequentially mediate the final glucosylation steps in crocin biosynthesis in G. jasminoides have been identified and functionally characterized. UGT75L6 preferentially glucosylates the carboxyl group of crocetin yielding crocetin glucosyl esters, while UGT94E5 glucosylates the 6' hydroxyl group of the glucose moiety of crocetin glucosyl esters. The expression pattern of neither UGT75L6 nor UGT94E5 correlated with the pattern of crocin accumulation in G. jasminoides.
Copyright © 2012 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.

Entities:  

Mesh:

Substances:

Year:  2012        PMID: 22569263     DOI: 10.1016/j.febslet.2012.03.003

Source DB:  PubMed          Journal:  FEBS Lett        ISSN: 0014-5793            Impact factor:   4.124


  16 in total

1.  Candidate Enzymes for Saffron Crocin Biosynthesis Are Localized in Multiple Cellular Compartments.

Authors:  Olivia Costantina Demurtas; Sarah Frusciante; Paola Ferrante; Gianfranco Diretto; Noraddin Hosseinpour Azad; Marco Pietrella; Giuseppe Aprea; Anna Rita Taddei; Elena Romano; Jianing Mi; Salim Al-Babili; Lorenzo Frigerio; Giovanni Giuliano
Journal:  Plant Physiol       Date:  2018-05-29       Impact factor: 8.340

Review 2.  Crocins for Ischemic Stroke: A Review of Current Evidence.

Authors:  Kiran Shahbaz; Dennis Chang; Xian Zhou; Mitchell Low; Sai Wang Seto; Chung Guang Li
Journal:  Front Pharmacol       Date:  2022-08-05       Impact factor: 5.988

3.  Integrated SMRT and Illumina Sequencing Provide New Insights into Crocin Biosynthesis of Gardenia jasminoides.

Authors:  Tengfei Shen; Yongjie Zheng; Qian Liu; Caihui Chen; Lili Huang; Shaoyong Deng; Meng Xu; Chunxia Yang
Journal:  Int J Mol Sci       Date:  2022-06-05       Impact factor: 6.208

4.  Novel carotenoid cleavage dioxygenase catalyzes the first dedicated step in saffron crocin biosynthesis.

Authors:  Sarah Frusciante; Gianfranco Diretto; Mark Bruno; Paola Ferrante; Marco Pietrella; Alfonso Prado-Cabrero; Angela Rubio-Moraga; Peter Beyer; Lourdes Gomez-Gomez; Salim Al-Babili; Giovanni Giuliano
Journal:  Proc Natl Acad Sci U S A       Date:  2014-08-05       Impact factor: 11.205

5.  Six Uridine-Diphosphate Glycosyltransferases Catalyze the Glycosylation of Bioactive C13-Apocarotenols.

Authors:  Guangxin Sun; Natalia Putkaradze; Sina Bohnacker; Rafal Jonczyk; Tarik Fida; Thomas Hoffmann; Rita Bernhardt; Katja Härtl; Wilfried Schwab
Journal:  Plant Physiol       Date:  2020-10-05       Impact factor: 8.340

6.  The chromosome-level Stevia genome provides insights into steviol glycoside biosynthesis.

Authors:  Xiaoyang Xu; Haiyan Yuan; Xiaqing Yu; Suzhen Huang; Yuming Sun; Ting Zhang; Qingquan Liu; Haiying Tong; Yongxia Zhang; Yinjie Wang; Chunxiao Liu; Lei Wu; Menglan Hou; Yongheng Yang
Journal:  Hortic Res       Date:  2021-06-01       Impact factor: 6.793

7.  Calcium/calmodulin alleviates substrate inhibition in a strawberry UDP-glucosyltransferase involved in fruit anthocyanin biosynthesis.

Authors:  Hui Peng; Tianbao Yang; Bruce D Whitaker; Lingfei Shangguan; Jinggui Fang
Journal:  BMC Plant Biol       Date:  2016-09-08       Impact factor: 4.215

8.  The Accumulation of Crocin and Geniposide and Transcripts of Phytoene Synthase during Maturation of Gardenia jasminoides Fruit.

Authors:  Lan Gao; Bi-Yun Zhu
Journal:  Evid Based Complement Alternat Med       Date:  2013-03-24       Impact factor: 2.629

9.  Structural characterization of highly glucosylated crocins and regulation of their biosynthesis during flower development in Crocus.

Authors:  Oussama Ahrazem; Angela Rubio-Moraga; Maria L Jimeno; Lourdes Gómez-Gómez
Journal:  Front Plant Sci       Date:  2015-11-04       Impact factor: 5.753

10.  Identification of a Flavonoid Glucosyltransferase Involved in 7-OH Site Glycosylation in Tea plants (Camellia sinensis).

Authors:  Xinlong Dai; Juhua Zhuang; Yingling Wu; Peiqiang Wang; Guifu Zhao; Yajun Liu; Xiaolan Jiang; Liping Gao; Tao Xia
Journal:  Sci Rep       Date:  2017-07-19       Impact factor: 4.379

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.