Literature DB >> 22568015

[Change of the lipid parameters in the murine liver during one month after low intensity X-ray exposure at low doses].

M A Klimovich, M V Kozlov, L N Shishkina.   

Abstract

Parameters of the physicochemical regulatory system of lipid peroxidation in the liver of white outbred mice (females) were studied before and during one month after X-ray exposure at the doses less than 1.5 mGy in the autumn and spring-summer seasons. The initial value of parameters is found to exert the most substantial influence on the liver relative mass, the phosphatidylcholine and lysoform relative content in the liver phospholipids of mice. The reliable diminution and the substantial influence of the dose rate dynamics during irradiation are revealed for the molar ratio of [sterols]/[phospholipids], the phosphatidylcholine/phosphatidylethanolamine ratio and the ratio of sums of the more easily oxidizable to the more poorly oxidizable fractions ofphospolipids. The experimental data testify to the complicated nonlinear character of the biological effects of X-irradiation at low doses.

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Year:  2012        PMID: 22568015

Source DB:  PubMed          Journal:  Radiats Biol Radioecol        ISSN: 0869-8031


  1 in total

1.  Metabolomic changes in gastrointestinal tissues after whole body radiation in a murine model.

Authors:  Sanchita P Ghosh; Rajbir Singh; Kushal Chakraborty; Shilpa Kulkarni; Arushi Uppal; Yue Luo; Prabhjit Kaur; Rupak Pathak; K Sree Kumar; Martin Hauer-Jensen; Amrita K Cheema
Journal:  Mol Biosyst       Date:  2013-02-13
  1 in total

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