Toshiro Obuchi1, Takao Saito, Akinori Iwasaki. 1. Department of Thoracic Surgery, St. Mary's Hospital, Tsubuku-hon-machi 422, Kurume, Japan. fukuoka_obuchi@yahoo.co.jp
Abstract
OBJECTIVE: We examined whether cancers frequently occur in hemodialysis patients, and therefore, investigated the features and outcomes of hemodialysis patients who had undergone surgery for non-small cell lung cancer. METHODS: Between 1995 and 2011, 14 hemodialysis patients with lung cancer (8 males and 6 females) with a mean age of 67.0 years successfully underwent pulmonary resection at our institution. We investigated the 5-year survival rate and causes of death. The occurrence of multiple primary cancers in our patients and other lung-cancer patients reported in the articles were statistically compared by Chi-square test. A p value <0.05 was considered to be statistically significant. RESULTS: The 5-year survival rate was 47.3 %, and six patients had died before our investigation. Four of the six had died of non-cancerous diseases related to hemodialysis. Five of 14 patients had a history of other primary cancers in other organs, and this incidence rate of multiple primary cancers was significantly higher than in other lung-cancer patients (p = 0.0071). CONCLUSION: The frequency of cancer in hemodialysis patients can be underestimated because of their early deaths by non-cancerous diseases. However, the incidence rate of multiple primary cancers may represent a unique characteristic of such patients.
OBJECTIVE: We examined whether cancers frequently occur in hemodialysis patients, and therefore, investigated the features and outcomes of hemodialysis patients who had undergone surgery for non-small cell lung cancer. METHODS: Between 1995 and 2011, 14 hemodialysis patients with lung cancer (8 males and 6 females) with a mean age of 67.0 years successfully underwent pulmonary resection at our institution. We investigated the 5-year survival rate and causes of death. The occurrence of multiple primary cancers in our patients and other lung-cancerpatients reported in the articles were statistically compared by Chi-square test. A p value <0.05 was considered to be statistically significant. RESULTS: The 5-year survival rate was 47.3 %, and six patients had died before our investigation. Four of the six had died of non-cancerous diseases related to hemodialysis. Five of 14 patients had a history of other primary cancers in other organs, and this incidence rate of multiple primary cancers was significantly higher than in other lung-cancerpatients (p = 0.0071). CONCLUSION: The frequency of cancer in hemodialysis patients can be underestimated because of their early deaths by non-cancerous diseases. However, the incidence rate of multiple primary cancers may represent a unique characteristic of such patients.
Authors: P Maisonneuve; L Agodoa; R Gellert; J H Stewart; G Buccianti; A B Lowenfels; R A Wolfe; E Jones; A P Disney; D Briggs; M McCredie; P Boyle Journal: Lancet Date: 1999-07-10 Impact factor: 79.321
Authors: John H Stewart; Gherardo Buccianti; Lawrence Agodoa; Ryszard Gellert; Margaret R E McCredie; Albert B Lowenfels; Alex P S Disney; Robert A Wolfe; Peter Boyle; Patrick Maisonneuve Journal: J Am Soc Nephrol Date: 2003-01 Impact factor: 10.121