Literature DB >> 22564661

Stereoselective synthesis of pentacyclic steroids functionalized at C-11.

Malika Ibrahim-Ouali1, Eugénie Romero, Khalil Hamze.   

Abstract

We set out to describe an efficient and versatile method for preparing pentacyclic steroids diversely substituted at C-11 from cholic acid, via a stereoselective epoxidation and the epoxide opening as the key steps. The characteristic (1)H and (13)C NMR spectroscopic features of the synthesized compounds are reported.
Copyright © 2012. Published by Elsevier Inc.

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Year:  2012        PMID: 22564661     DOI: 10.1016/j.steroids.2012.04.004

Source DB:  PubMed          Journal:  Steroids        ISSN: 0039-128X            Impact factor:   2.668


  1 in total

1.  Novel d-Annulated Pentacyclic Steroids: Regioselective Synthesis and Biological Evaluation in Breast Cancer Cells.

Authors:  Svetlana K Vorontsova; Anton V Yadykov; Alexander M Scherbakov; Mikhail E Minyaev; Igor V Zavarzin; Ekaterina I Mikhaevich; Yulia A Volkova; Valerii Z Shirinian
Journal:  Molecules       Date:  2020-07-31       Impact factor: 4.411

  1 in total

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