Literature DB >> 22564500

Methodologists and context experts disagreed regarding managing conflicts of interest of clinical practice guidelines panels.

Elie A Akl1, Renee Karl, Gordon H Guyatt.   

Abstract

OBJECTIVE: A new strategy to manage conflicts of interests (COIs) of a clinical guideline's panelists gives primary responsibility to a methodologist, puts equal emphasis on intellectual and financial COIs, and excludes panelists with primary conflicts from drafting or voting on recommendations. We explored the views of the methodologists and content experts regarding the new strategy. STUDY DESIGN AND
SETTING: Before the guidelines chapter panels initiated their work, we conducted semi-structured personal interviews with the methodologists and the lead content experts. We analyzed the data qualitatively.
RESULTS: Twenty-four panelists participated. The methodologists thought that the new strategy increased their responsibility and authority. The lead content experts perceived their role label as unfair and reflecting a demotion. Whereas methodologists were concerned about potential conflicts with content experts, the lead content experts were uncomfortable with the "extra surveillance" by the methodologists. Whereas methodologists believed that the changes ensure more rigorous evidence-based guidelines, some lead content experts were worried that methodologists' lack of content expertise and content expert attrition could hurt the quality of the guidelines.
CONCLUSIONS: The methodologists and lead content experts were uneasy regarding their counterpart's role. They disagreed about the potential effect of the new strategy on the quality of the guideline.
Copyright © 2012 Elsevier Inc. All rights reserved.

Mesh:

Year:  2012        PMID: 22564500     DOI: 10.1016/j.jclinepi.2011.12.013

Source DB:  PubMed          Journal:  J Clin Epidemiol        ISSN: 0895-4356            Impact factor:   6.437


  5 in total

1.  Contributors to primary care guidelines: What are their professions and how many of them have conflicts of interest?

Authors:  G Michael Allan; Roni Kraut; Aven Crawshay; Christina Korownyk; Ben Vandermeer; Michael R Kolber
Journal:  Can Fam Physician       Date:  2015-01       Impact factor: 3.275

Review 2.  Conflicts of interest disclosure forms and management in critical care clinical practice guidelines.

Authors:  Waleed Alhazzani; Kimberley Lewis; Roman Jaeschke; Bram Rochwerg; Morten Hylander Møller; Laura Evans; Kevin C Wilson; Sheena Patel; Craig M Coopersmith; Maurizio Cecconi; Gordon Guyatt; Elie A Akl
Journal:  Intensive Care Med       Date:  2018-09-27       Impact factor: 17.440

Review 3.  Evidence base in guideline generation in diabetes.

Authors:  I Mühlhauser; G Meyer
Journal:  Diabetologia       Date:  2013-03-09       Impact factor: 10.122

4.  Managing conflicts of interest in the UK National Institute for Health and Care Excellence (NICE) clinical guidelines programme: qualitative study.

Authors:  Tanya Graham; Phil Alderson; Tim Stokes
Journal:  PLoS One       Date:  2015-03-26       Impact factor: 3.240

5.  Influence and management of conflicts of interest in randomised clinical trials: qualitative interview study.

Authors:  Lasse Østengaard; Andreas Lundh; Tine Tjørnhøj-Thomsen; Suhayb Abdi; Mustafe H A Gelle; Lesley A Stewart; Isabelle Boutron; Asbjørn Hróbjartsson
Journal:  BMJ       Date:  2020-10-27
  5 in total

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