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Literature DB >> 22562778

Convergent synthesis of the pentasaccharide repeating unit of the O-antigenic polysaccharide of enterohaemorrhagic Escherichia coli O113.

Abstract

An acidic pentasaccharide repeating unit corresponding to the O-antigenic polysaccharide of enterohaemorrhagic Escherichia coli O113 as its p-methoxyphenyl glycoside has been synthesized in a convergent manner by adopting a [3+2] block glycosylation strategy. During the synthetic endeavor a one-pot reaction condition for stereoselective glycosylation and protecting group manipulation has been applied. All glycosylation steps are highly stereoselective with good to excellent yield.

Entities: Chemical Species

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Year: 2012 PMID： 22562778 DOI： 10.1007/s10719-012-9383-4

Source DB: PubMed Journal: Glycoconj J ISSN： 0282-0080 Impact factor: 2.916

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References

17 in total

1. Perchloric acid adsorbed on silica gel as a new, highly efficient, and versatile catalyst for acetylation of phenols, thiols, alcohols, and amines.

Authors: Asit K Chakraborti; Rajesh Gulhane
Journal: Chem Commun (Camb) Date: 2003-08-07 Impact factor: 6.222

2. Convergent synthesis of a common pentasaccharide corresponding to the O-antigen of Escherichia coli O168 and Shigella dysenteriae type 4.

Authors: Goutam Guchhait; Anup Kumar Misra
Journal: Glycoconj J Date: 2010-12-22 Impact factor: 2.916

3. Total synthesis of antigen bacillus anthracis tetrasaccharide--creation of an anthrax vaccine candidate.

Authors: Daniel B Werz; Peter H Seeberger
Journal: Angew Chem Int Ed Engl Date: 2005-10-07 Impact factor: 15.336

Review 4. Escherichia coli O157:H7 and the hemolytic-uremic syndrome.

Authors: T G Boyce; D L Swerdlow; P M Griffin
Journal: N Engl J Med Date: 1995-08-10 Impact factor: 91.245

5. Shiga toxin-producing Escherichia coli infection and antibodies against Stx2 and Stx1 in household contacts of children with enteropathic hemolytic-uremic syndrome.

Authors: Kerstin Ludwig; Volkan Sarkim; Martin Bitzan; Mohamed A Karmali; Christoph Bobrowski; Hans Ruder; Rainer Laufs; Ingo Sobottka; Martin Petric; Helge Karch; Dirk E Müller-Wiefel
Journal: J Clin Microbiol Date: 2002-05 Impact factor: 5.948

Review 10. Enterohemorrhagic Escherichia coli.

Authors: J B Kaper
Journal: Curr Opin Microbiol Date: 1998-02 Impact factor: 7.934

Convergent synthesis of the pentasaccharide repeating unit of the O-antigenic polysaccharide of enterohaemorrhagic Escherichia coli O113.

1. Perchloric acid adsorbed on silica gel as a new, highly efficient, and versatile catalyst for acetylation of phenols, thiols, alcohols, and amines.

2. Convergent synthesis of a common pentasaccharide corresponding to the O-antigen of Escherichia coli O168 and Shigella dysenteriae type 4.

3. Total synthesis of antigen bacillus anthracis tetrasaccharide--creation of an anthrax vaccine candidate.

Review 4. Escherichia coli O157:H7 and the hemolytic-uremic syndrome.

5. Shiga toxin-producing Escherichia coli infection and antibodies against Stx2 and Stx1 in household contacts of children with enteropathic hemolytic-uremic syndrome.

6. New trends in carbohydrate-based vaccines.

7. A concise synthesis of the 6-O- and 6'-O-sulfated analogues of the sialyl Lewis X tetrasaccharide.

Review 8. The structures of Escherichia coli O-polysaccharide antigens.

Review 9. Enterohaemorrhagic Escherichia coli in human medicine.

Review 10. Enterohemorrhagic Escherichia coli.