| Literature DB >> 2256195 |
J P Droz1, M Schlumberger, P Rougier, M Ghosn, P Gardet, C Parmentier.
Abstract
Forty-nine patients with metastatic nonanaplastic thyroid carcinoma were treated over a 10-year period. Five successive chemotherapeutic protocols were used: a combination of doxorubicin, etoposide, 5-fluorouracil and cyclophosphamide; elliptinium acetate; doxorubicin; cisplatin; and the combination of doxorubicin and cisplatin. Results obtained with the different protocols were very disappointing, with only two objective responses (3%). Phase II trials with new chemotherapeutic agents are warranted in selected cases of nonanaplastic metastatic thyroid carcinoma.Entities:
Mesh:
Year: 1990 PMID: 2256195 DOI: 10.1177/030089169007600513
Source DB: PubMed Journal: Tumori ISSN: 0300-8916