BACKGROUND: Sleep is critical for optimal cognitive function, but as we age both cognitive impairment and sleep problems increase. Longitudinal, population-based studies can be used to investigate temporal relationships between sleep and cognition. METHODS: A total of 2012 cognitively unimpaired individuals 65 years and over were drawn from the MRC Cognitive Function and Ageing Study (CFAS). They answered self-reported measures including: insomnia symptoms and age of onset, night time wakings, snoring, sleep onset latency, napping, daytime sleepiness and duration of night time sleep. Cognition was measured via the Mini-Mental State Examination. RESULTS: It was found that daytime napping at baseline was associated with a lower risk of cognitive decline at two and 10 years, and that obtaining ≤6.5h of night-time sleep and excessive daytime sleepiness at baseline were associated with an increased risk at 10 years. CONCLUSIONS: Daytime napping, night-time sleep duration, and excessive daytime sleepiness may be modifiable behaviours open to intervention strategies, or, clinical indicators of future decline in older individuals. Crown
BACKGROUND: Sleep is critical for optimal cognitive function, but as we age both cognitive impairment and sleep problems increase. Longitudinal, population-based studies can be used to investigate temporal relationships between sleep and cognition. METHODS: A total of 2012 cognitively unimpaired individuals 65 years and over were drawn from the MRC Cognitive Function and Ageing Study (CFAS). They answered self-reported measures including: insomnia symptoms and age of onset, night time wakings, snoring, sleep onset latency, napping, daytime sleepiness and duration of night time sleep. Cognition was measured via the Mini-Mental State Examination. RESULTS: It was found that daytime napping at baseline was associated with a lower risk of cognitive decline at two and 10 years, and that obtaining ≤6.5h of night-time sleep and excessive daytime sleepiness at baseline were associated with an increased risk at 10 years. CONCLUSIONS: Daytime napping, night-time sleep duration, and excessive daytime sleepiness may be modifiable behaviours open to intervention strategies, or, clinical indicators of future decline in older individuals. Crown
Authors: Kristine Yaffe; Ilya Nasrallah; Tina D Hoang; Diane S Lauderdale; Kristen L Knutson; Mercedes R Carnethon; Lenore J Launer; Cora E Lewis; Stephen Sidney Journal: Sleep Date: 2016-09-01 Impact factor: 5.849
Authors: Ricardo S Osorio; Tyler Gumb; Elizabeth Pirraglia; Andrew W Varga; Shou-En Lu; Jason Lim; Margaret E Wohlleber; Emma L Ducca; Viachaslau Koushyk; Lidia Glodzik; Lisa Mosconi; Indu Ayappa; David M Rapoport; Mony J de Leon Journal: Neurology Date: 2015-04-15 Impact factor: 9.910
Authors: Calliope Holingue; Alexandra Wennberg; Slava Berger; Vsevolod Y Polotsky; Adam P Spira Journal: Metabolism Date: 2018-02-01 Impact factor: 8.694
Authors: Adam P Spira; Yang An; Mark N Wu; Jocelynn T Owusu; Eleanor M Simonsick; Murat Bilgel; Luigi Ferrucci; Dean F Wong; Susan M Resnick Journal: Sleep Date: 2018-10-01 Impact factor: 5.849
Authors: Adam P Spira; Christopher E Gonzalez; Vijay K Venkatraman; Mark N Wu; Jennifer Pacheco; Eleanor M Simonsick; Luigi Ferrucci; Susan M Resnick Journal: Sleep Date: 2016-05-01 Impact factor: 5.849