| Literature DB >> 22560209 |
Robert V Farese1, Rudolf Zechner, Christopher B Newgard, Tobias C Walther.
Abstract
Excessive deposition of fat in the liver (hepatic steatosis) is frequently accompanied by hepatic insulin resistance. Whether this correlation is due to a causal relationship between the conditions has been the subject of considerable debate, and the literature abounds with conflicting data and theories. Here we provide a perspective by defining the problem and its challenges, analyzing the possible causative relationships, and drawing some conclusions.Entities:
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Year: 2012 PMID: 22560209 PMCID: PMC3767424 DOI: 10.1016/j.cmet.2012.03.004
Source DB: PubMed Journal: Cell Metab ISSN: 1550-4131 Impact factor: 27.287