Literature DB >> 22560070

Autoimmune T cells lured to a FASL web of death by MSCs.

William J Murphy1, Jan A Nolta.   

Abstract

Achieving immune tolerance through cell transplantation is a promising approach for treating autoimmune disease. In this issue of Cell Stem Cell, Akiyama et al. (2012) demonstrate that human and mouse mesenchymal stem cells can induce immune suppression by attracting and killing autoreactive T cells, which stimulates TGFb production by macrophages and generates regulatory T cells.
Copyright © 2012 Elsevier Inc. All rights reserved.

Entities:  

Year:  2012        PMID： 22560070     DOI： 10.1016/j.stem.2012.04.013

Source DB:  PubMed          Journal:  Cell Stem Cell        ISSN： 1875-9777            Impact factor:   24.633


  4 in total

Review 1.  Genetically engineered mesenchymal stromal cells as a new trend for treatment of severe acute graft-versus-host disease.

Authors:  Sanaz Keshavarz Shahbaz; Amir Hossein Mansourabadi; Davood Jafari
Journal:  Clin Exp Immunol       Date:  2022-05-13       Impact factor: 4.330

2.  Knockdown of MicroRNA Let-7a Improves the Functionality of Bone Marrow-Derived Mesenchymal Stem Cells in Immunotherapy.

Authors:  Yang Yu; Li Liao; Bingyi Shao; Xiaoxia Su; Yi Shuai; Han Wang; Fengqing Shang; Zhifei Zhou; Deqin Yang; Yan Jin
Journal:  Mol Ther       Date:  2016-12-28       Impact factor: 12.910

3.  Genetically engineered mesenchymal stromal cells as a new trend for treatment of severe acute graft-versus-host disease.

Authors:  Sanaz Keshavarz Shahbaz; Amir Hossein Mansourabadi; Davood Jafari
Journal:  Clin Exp Immunol       Date:  2022-02-08       Impact factor: 5.732

4.  Mesenchymal stem cells derived from human iPS cells via mesoderm and neuroepithelium have different features and therapeutic potentials.

Authors:  Shinya Eto; Mizuki Goto; Minami Soga; Yumi Kaneko; Yusuke Uehara; Hiroshi Mizuta; Takumi Era
Journal:  PLoS One       Date:  2018-07-25       Impact factor: 3.240
  4 in total

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