Literature DB >> 2255913

Requirement of ets-2 expression for Xenopus oocyte maturation.

Z Q Chen1, L A Burdett, A K Seth, J A Lautenberger, T S Papas.   

Abstract

A molecular clone of the Xenopus laevis ets-2 gene was isolated from an oocyte complementary DNA library. The amount of messenger RNA (mRNA) in each oocyte or embryo was almost constant during oogenesis and was maintained until the blastula stage of embryonic development, indicating that the observed 3.2-kilobase transcript is a maternal message. The only normal adult tissue in which ets-2 mRNA was detected was the ovary. Injection of antisense oligonucleotides homologous to the ets-2 sequence into oocytes led to degradation of the mRNA and blocked hormone-induced germinal vesicle breakdown. The ets-2 product is thus required for the meiotic maturation of Xenopus oocytes.

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Year:  1990        PMID： 2255913     DOI： 10.1126/science.2255913

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  10 in total

1.  Characterization of the cDNA sequences of two Xenopus ets-2 proto-oncogenes.

Authors:  L A Burdett; S Qi; Z Q Chen; J A Lautenberger; T S Papas
Journal:  Nucleic Acids Res       Date:  1992-01-25       Impact factor: 16.971

2.  Transcription inhibition of the somatic-type phosphoglycerate kinase 1 gene in vitro by a testis-specific factor that recognizes a sequence similar to the binding site for Ets oncoproteins.

Authors:  M Goto; T Tamura; K Mikoshiba; Y Masamune; Y Nakanishi
Journal:  Nucleic Acids Res       Date:  1991-07-25       Impact factor: 16.971

3.  Identification of a second promoter in the human c-ets-2 proto-oncogene.

Authors:  A Bègue; P Crepieux; N Vu-Dac; A Hautefeuille; N Spruyt; V Laudet; D Stehelin
Journal:  Gene Expr       Date:  1997

4.  The ets multigene family is conserved throughout the Metazoa.

Authors:  B M Degnan; S M Degnan; T Naganuma; D E Morse
Journal:  Nucleic Acids Res       Date:  1993-07-25       Impact factor: 16.971

5.  The Ets2 transcription factor inhibits apoptosis induced by colony-stimulating factor 1 deprivation of macrophages through a Bcl-xL-dependent mechanism.

Authors:  L Sevilla; C Aperlo; V Dulic; J C Chambard; C Boutonnet; O Pasquier; P Pognonec; K E Boulukos
Journal:  Mol Cell Biol       Date:  1999-04       Impact factor: 4.272

6.  Microinjection of in vitro transcribed RNA and antisense oligonucleotides in mouse oocytes and early embryos to study the gain- and loss-of-function of genes.

Authors:  I Kola; S H Sumarsono
Journal:  Mol Biotechnol       Date:  1996-10       Impact factor: 2.695

7.  The Ets1 transcription factor is widely expressed during murine embryo development and is associated with mesodermal cells involved in morphogenetic processes such as organ formation.

Authors:  I Kola; S Brookes; A R Green; R Garber; M Tymms; T S Papas; A Seth
Journal:  Proc Natl Acad Sci U S A       Date:  1993-08-15       Impact factor: 11.205

8.  XrpFI, an amphibian transcription factor composed of multiple polypeptides immunologically related to the GA-binding protein alpha and beta subunits, is differentially expressed during Xenopus laevis development.

Authors:  M Marchioni; S Morabito; A L Salvati; E Beccari; F Carnevali
Journal:  Mol Cell Biol       Date:  1993-10       Impact factor: 4.272

9.  One of two Ets-binding sites in the cytokeratin EndoA enhancer is essential for enhancer activity and binds to Ets-2 related proteins.

Authors:  Y Fujimura; H Yamamoto; F Hamazato; M Nozaki
Journal:  Nucleic Acids Res       Date:  1994-02-25       Impact factor: 16.971

10.  The maternal store of zinc finger protein encoding mRNAs in fully grown Xenopus oocytes is not required for early embryogenesis.

Authors:  T el-Baradi; T Bouwmeester; R Giltay; T Pieler
Journal:  EMBO J       Date:  1991-06       Impact factor: 11.598
  10 in total

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