Literature DB >> 22557305

Hypoglycemic effect of Gymnema sylvestre (retz.,) R.Br leaf in normal and alloxan induced diabetic rats.

S Sathya1, R Kokilavani, K Gurusamy.   

Abstract

The water extract of Gymnema sylvestre R.Br leaf was tested for hypoglycemic activity in normal and alloxan induced diabetic rats. Grated amount (2ml/kg) of the water extract of Gymnema sylvestre leaf was given to both normal and alloxan induced diabetic rats. A significant reduction of glucose concentration was noticed in normal rats, blood glucose level was significantly reduced in diabetic rats. Protein level is also decreased in diabetic rats. Urea, uric acid and creatinine levels were increased in diabetic condition. After the herbal treatment the levels were altered near to normal level.

Entities:  

Keywords:  Alloxan induced diabetic rats; Biochemical parameters; Blood glucose; Gymnema sylvestre; Protein levels; hypoglycemic activity

Year:  2008        PMID： 22557305      PMCID： PMC3336356     

Source DB:  PubMed          Journal:  Anc Sci Life        ISSN： 0257-7941


  3 in total

1.  Hypolipidaemic Effects of Gymnema sylvestre on High Fat Diet Induced Dyslipidaemia in Wistar Rats.

Authors:  Dheeraj Kumar Singh; Narendra Kumar; Anjula Sachan; Preet Lakhani; Sachin Tutu; Rajendra Nath; Amod Kumar Sachan; Rakesh Kumar Dixit
Journal:  J Clin Diagn Res       Date:  2017-05-01

2.  Molecular identification, in vivo and in vitro activities of Calvatia gigantea (macro-fungus) as an antidiabetic agent.

Authors:  Omonike O Ogbole; Abraham O Nkumah; Augusta U Linus; Mofolusho O Falade
Journal:  Mycology       Date:  2019-03-31

Review 3.  Comprehensive Review on Phytochemicals, Pharmacological and Clinical Potentials of Gymnema sylvestre.

Authors:  Farzana Khan; Md Moklesur Rahman Sarker; Long Chiau Ming; Isa Naina Mohamed; Chao Zhao; Bassem Y Sheikh; Hiew Fei Tsong; Mohammad A Rashid
Journal:  Front Pharmacol       Date:  2019-10-29       Impact factor: 5.810
  3 in total

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