| Literature DB >> 22555364 |
K Krümpelmann1, T Hansen, W Fried-Proell, M Habekost, D Flieger, S Sommer, C J Kirkpatrick.
Abstract
Goblet cell carcinoids are biphasic neoplasms of the gastrointestinal tract composed of a glandular and neuroendocrine differentiation. Typically, goblet cell carcinoids are localized in the vermiform appendix. We report the case of a 60-year-old female patient with the diagnosis of a 1.2-cm rectal goblet cell carcinoid tumor discovered during prophylactic proctocolonoscopy. Because of the known aggressive behavior of this entity, a rectosigmoidectomy was performed. The preoperative staging revealed neither local nor systemic spread. After 8 months, the patient is in good health. As a primary tumor of the extraappendiceal gastrointestinal tract, goblet cell carcinoids are a rarity. It is generally recommended to exclude metastasis of a primary appendiceal neoplasm. However, since the patient underwent an appendectomy in 1974, primary origin in the rectum is favored.Entities:
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Year: 2013 PMID: 22555364 DOI: 10.1007/s00292-012-1590-z
Source DB: PubMed Journal: Pathologe ISSN: 0172-8113 Impact factor: 1.011