Literature DB >> 225549

Polyoma DNA synthesis in isolated nuclei: evidence for defective replication forks.

G Bjursell, V Munck, A J Therkelsen.   

Abstract

Nuclei, isolated from polyoma virus-infected mouse 3T6 cells, were incubated under condtions suitable for polyoma DNA synthesis. By using electrom microscopy and standard regression statistics, it was shown that replication is mainly unidirectional in a large number of molecules, indicating the presence of inactive replication forks. The replication forks were inactivated randomly, and the defect seemed to be present from the beginning of the in vitro incubation.

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Year:  1979        PMID: 225549      PMCID: PMC353405     

Source DB:  PubMed          Journal:  J Virol        ISSN: 0022-538X            Impact factor:   5.103


  21 in total

1.  Strandedness of newly synthesized short pieces of polyoma DNA from isolated nuclei.

Authors:  P J Flory
Journal:  Nucleic Acids Res       Date:  1977       Impact factor: 16.971

2.  Effects of 2'-deoxy-2'-azidocytidine on polyoma virus DNA replication: evidence for rolling circle-type mechanism.

Authors:  G Bjursell
Journal:  J Virol       Date:  1978-04       Impact factor: 5.103

3.  Replication of polyoma DNA accumlation of early replicative intermediates during hydroxyurea inhibition.

Authors:  G Bjursell; G Magnusson
Journal:  Virology       Date:  1976-10-01       Impact factor: 3.616

4.  Asymmetric Okazaki piece synthesis during replication of simian virus 40 DNA in vivo.

Authors:  D Perlman; J A Huberman
Journal:  Cell       Date:  1977-12       Impact factor: 41.582

Review 5.  From deoxynucleotides to DNA synthesis.

Authors:  P Reichard
Journal:  Fed Proc       Date:  1978-01

6.  In vitro polyoma DNA synthesis: asymmetry of short DNA chains.

Authors:  T Hunter; B Francke; L Bacheler
Journal:  Cell       Date:  1977-12       Impact factor: 41.582

7.  2'-Deoxy-2'-azidocytidine inhibits the initiation of polyoma DNA synthesis.

Authors:  G Bjursell; L Skoog; L Thelander; G Söderman
Journal:  Proc Natl Acad Sci U S A       Date:  1977-12       Impact factor: 11.205

Review 8.  Structure of chromatin.

Authors:  R D Kornberg
Journal:  Annu Rev Biochem       Date:  1977       Impact factor: 23.643

9.  The replication of polyoma DNA.

Authors:  L V Crawford; C Syrett; A Wilde
Journal:  J Gen Virol       Date:  1973-12       Impact factor: 3.891

10.  2'-Deoxy-2'-azidocytidine, a new inhibitor of DNA replication in mammalian cells.

Authors:  L Skoog; G Bjursell; L Thelander; T Hägerström; J Hobbs; F Eckstein
Journal:  Eur J Biochem       Date:  1977-01
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  3 in total

1.  Asynchronous bidirectional replication of polyoma virus DNA.

Authors:  A J Buckler-White; M R Krauss; V Pigiet; R M Benbow
Journal:  J Virol       Date:  1982-09       Impact factor: 5.103

2.  Synthesis of multimeric polyoma virus DNA in mouse L-cells: role of the tsA1S9 gene product.

Authors:  P R Ganz; R Sheinin
Journal:  J Virol       Date:  1983-06       Impact factor: 5.103

3.  Distribution of replicating simian virus 40 DNA in intact cells and its maturation in isolated nuclei.

Authors:  D P Tapper; S Anderson; M L DePamphilis
Journal:  J Virol       Date:  1982-03       Impact factor: 5.103

  3 in total

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