| Literature DB >> 22553903 |
Abstract
The total synthesis of (±)-sorocenol B has been accomplished featuring key steps including silver nanoparticle (AgNP)-catalyzed Diels-Alder cycloaddition and late-stage Pd(II)-catalyzed oxidative cyclization. The synthetic natural product exhibited low micromolar cytotoxic activity against a number of human cancer cell lines.Entities:
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Year: 2012 PMID: 22553903 PMCID: PMC3434240 DOI: 10.1021/ol300800r
Source DB: PubMed Journal: Org Lett ISSN: 1523-7052 Impact factor: 6.005