Literature DB >> 22553573

Visual acuity loss and OCT changes as initial signs of leukaemia.

Jose M Ortiz1, Jose M Ruiz-Moreno, Paola Pozo-Martos, Javier A Montero.   

Abstract

AIM: To report two cases where decreased visual acuity was the first symptom of leukaemia and optical coherence tomography (OCT) allowed identification and localization of the retinal lesions.
METHODS: Retrospective, interventional, case reports.
RESULTS: One case of lymphoblastic acute leukaemia and chronic lymphoid leukaemia were diagnosed following decreased visual acuity. OCT showed macular serous detachment in the first case. The second case presented hypo fluorescent retinal infiltrates which appeared as hyper reflective lesions by OCT. Retinal changes disappeared and visual acuity was recovered following complete remission of the neoplasm.
CONCLUSION: OCT is a valuable, non invasive diagnostic tool permitting detection, localization and follow-up of ocular dissemination of neoplasms.

Entities:  

Keywords:  acute lymphoblastic leukaemia; chronic lymphoid leukaemia; optical coherence tomography

Year:  2010        PMID: 22553573      PMCID: PMC3340619          DOI: 10.3980/j.issn.2222-3959.2010.03.24

Source DB:  PubMed          Journal:  Int J Ophthalmol        ISSN: 2222-3959            Impact factor:   1.779


  6 in total

Review 1.  Serous detachment of the retina.

Authors:  Richard F Spaide; Mauro Goldbaum; Doric W K Wong; Kong Chan Tang; Tomohiro Iida
Journal:  Retina       Date:  2003-12       Impact factor: 4.256

2.  Acute lymphoblastic leukemia presenting as bilateral serous macular detachments.

Authors:  Tamara K Fackler; Srilaxmi Bearelly; Terry Odom; Sharon Fekrat; Michael J Cooney
Journal:  Retina       Date:  2006 Jul-Aug       Impact factor: 4.256

Review 3.  [Ocular sites of acute leukemias].

Authors:  C Berthou; S Roncin; J Colin; J F Abgrall
Journal:  J Fr Ophtalmol       Date:  1996       Impact factor: 0.818

4.  Ocular manifestations of leukemia: leukemic infiltration versus infectious process.

Authors:  K B Gordon; H S Rugo; J L Duncan; A R Irvine; E L Howes; J M O'Brien; S R Carter
Journal:  Ophthalmology       Date:  2001-12       Impact factor: 12.079

Review 5.  [Bilateral serous detachment of neuroepithelium of the posterior pole disclosing acute leukemia].

Authors:  J M Riss; G Kaplanski; M Righini-Chossegros; J R Harle; P Escoffier; J B Saracco
Journal:  J Fr Ophtalmol       Date:  1990       Impact factor: 0.818

6.  Retinal fluorescein, indocyanine green angiography, and optic coherence tomography in non-Hodgkin primary intraocular lymphoma.

Authors:  Christine Fardeau; Cheryl P L Lee; Hélène Merle-Béral; Nathalie Cassoux; Bahram Bodaghi; Frédéric Davi; Phuc Lehoang
Journal:  Am J Ophthalmol       Date:  2009-02-25       Impact factor: 5.258

  6 in total
  1 in total

1.  Serous retinal detachment as a presenting sign of acute lymphoblastic leukemia: A case report and literature review.

Authors:  Malini Veerappan Pasricha; Natalia F Callaway; Quan Dong Nguyen; Diana V Do
Journal:  Am J Ophthalmol Case Rep       Date:  2021-06-22
  1 in total

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