Literature DB >> 22553501

Iron metabolism: interactions with normal and disordered erythropoiesis.

Tomas Ganz1, Elizabeta Nemeth.   

Abstract

Hemoglobinopathies and other disorders of erythroid cells are often associated with abnormal iron homeostasis. We review the molecular physiology of intracellular and systemic iron regulation, and the interactions between erythropoiesis and iron homeostasis. Finally, we discuss iron disorders that affect erythropoiesis as well as erythroid disorders that cause iron dysregulation.

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Year:  2012        PMID： 22553501      PMCID： PMC3331689          DOI： 10.1101/cshperspect.a011668

Source DB:  PubMed          Journal:  Cold Spring Harb Perspect Med        ISSN： 2157-1422            Impact factor:   6.915


  71 in total

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