Use of ganciclovir in the treatment of acquired cytomegalovirus disease in a preterm infant.

The first use of ganciclovir in a preterm infant is reported. The 27 week appropriate-for-gestational-age male infant developed a disseminated cytomegalovirus infection subsequent to a blood transfusion. A daily dose of 10 mg/kg administered intravenously in two divided doses for a total of 14 days was given without adverse clinical or toxic effects. The patient has remained well following discharge from hospital.