Literature DB >> 22553321

Partial escape of HIV-1 from cytotoxic T lymphocytes during chronic infection.

Martha J Lewis1, Mirabelle Dagarag, Basim Khan, Ayub Ali, Otto O Yang.   

Abstract

Viral mutational escape from CD8(+) cytotoxic T lymphocytes (CTLs) is typically considered to be a dichotomous process and uncommon during chronic HIV-1 infection. Ex vivo passaging of HIV-1 from persons with chronic infection, however, revealed the evolution of many fixed substitutions within and around CTL-targeted regions, with an associated increase in replicative capacity. This indicates an evolution of mutations during chronic HIV-1 infection that trade replicative fitness for incomplete evasion of CTLs, or "partial escape."

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Year:  2012        PMID： 22553321      PMCID： PMC3416319          DOI： 10.1128/JVI.06724-11

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  37 in total

1.  Codon-substitution models for heterogeneous selection pressure at amino acid sites.

Authors:  Z Yang; R Nielsen; N Goldman; A M Pedersen
Journal:  Genetics       Date:  2000-05       Impact factor: 4.562

2.  HIV-1 superinfection despite broad CD8+ T-cell responses containing replication of the primary virus.

Authors:  Marcus Altfeld; Todd M Allen; Xu G Yu; Mary N Johnston; Deepak Agrawal; Bette T Korber; David C Montefiori; David H O'Connor; Ben T Davis; Paul K Lee; Erica L Maier; Jason Harlow; Philip J R Goulder; Christian Brander; Eric S Rosenberg; Bruce D Walker
Journal:  Nature       Date:  2002-11-28       Impact factor: 49.962

3.  Variances of the average numbers of nucleotide substitutions within and between populations.

Authors:  M Nei; L Jin
Journal:  Mol Biol Evol       Date:  1989-05       Impact factor: 16.240

4.  Bi-specific monoclonal antibodies: selective binding and complement fixation to cells that express two different surface antigens.

Authors:  J T Wong; R B Colvin
Journal:  J Immunol       Date:  1987-08-15       Impact factor: 5.422

5.  Impaired processing and presentation of cytotoxic-T-lymphocyte (CTL) epitopes are major escape mechanisms from CTL immune pressure in human immunodeficiency virus type 1 infection.

Authors:  Yoshiyuki Yokomaku; Hideka Miura; Hiroko Tomiyama; Ai Kawana-Tachikawa; Masafumi Takiguchi; Asato Kojima; Yoshiyuki Nagai; Aikichi Iwamoto; Zene Matsuda; Koya Ariyoshi
Journal:  J Virol       Date:  2004-02       Impact factor: 5.103

6.  Epitope escape mutation and decay of human immunodeficiency virus type 1-specific CTL responses.

Authors:  Beth D Jamieson; Otto O Yang; Lance Hultin; Mary Ann Hausner; Patricia Hultin; Jose Matud; Kevin Kunstman; Scott Killian; John Altman; Kristina Kommander; Bette Korber; Janis Giorgi; Steven Wolinsky
Journal:  J Immunol       Date:  2003-11-15       Impact factor: 5.422

7.  Half-genome human immunodeficiency virus type 1 constructs for rapid production of reporter viruses.

Authors:  Ayub Ali; Beth D Jamieson; Otto O Yang
Journal:  J Virol Methods       Date:  2003-06-30       Impact factor: 2.014

8.  Clustered mutations in HIV-1 gag are consistently required for escape from HLA-B27-restricted cytotoxic T lymphocyte responses.

Authors:  A D Kelleher; C Long; E C Holmes; R L Allen; J Wilson; C Conlon; C Workman; S Shaunak; K Olson; P Goulder; C Brander; G Ogg; J S Sullivan; W Dyer; I Jones; A J McMichael; S Rowland-Jones; R E Phillips
Journal:  J Exp Med       Date:  2001-02-05       Impact factor: 14.307

9.  Immune selection for altered antigen processing leads to cytotoxic T lymphocyte escape in chronic HIV-1 infection.

Authors:  Rika Draenert; Sylvie Le Gall; Katja J Pfafferott; Alasdair J Leslie; Polan Chetty; Christian Brander; Edward C Holmes; Shih-Chung Chang; Margaret E Feeney; Marylyn M Addo; Lidia Ruiz; Danni Ramduth; Prakash Jeena; Marcus Altfeld; Stephanie Thomas; Yanhua Tang; Cori L Verrill; Catherine Dixon; Julia G Prado; Photini Kiepiela; Javier Martinez-Picado; Bruce D Walker; Philip J R Goulder
Journal:  J Exp Med       Date:  2004-04-05       Impact factor: 14.307

10.  Determinant of HIV-1 mutational escape from cytotoxic T lymphocytes.

Authors:  Otto O Yang; Phuong Thi Nguyen Sarkis; Ayub Ali; Jason D Harlow; Christian Brander; Spyros A Kalams; Bruce D Walker
Journal:  J Exp Med       Date:  2003-05-12       Impact factor: 14.307
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  5 in total

Review 1.  Genetic variation and HIV-associated neurologic disease.

Authors:  Satinder Dahiya; Bryan P Irish; Michael R Nonnemacher; Brian Wigdahl
Journal:  Adv Virus Res       Date:  2013       Impact factor: 9.937

2.  HIV-1 Epitope Variability Is Associated with T Cell Receptor Repertoire Instability and Breadth.

Authors:  Arumugam Balamurugan; Deon Claiborne; Hwee L Ng; Otto O Yang
Journal:  J Virol       Date:  2017-07-27       Impact factor: 5.103

3.  An elite controller of picornavirus infection targets an epitope that is resistant to immune escape.

Authors:  Michael P Bell; Danielle N Renner; Aaron J Johnson; Kevin D Pavelko
Journal:  PLoS One       Date:  2014-04-07       Impact factor: 3.240

4.  HIV-1 quasispecies delineation by tag linkage deep sequencing.

Authors:  Nicholas C Wu; Justin De La Cruz; Laith Q Al-Mawsawi; C Anders Olson; Hangfei Qi; Harding H Luan; Nguyen Nguyen; Yushen Du; Shuai Le; Ting-Ting Wu; Xinmin Li; Martha J Lewis; Otto O Yang; Ren Sun
Journal:  PLoS One       Date:  2014-05-19       Impact factor: 3.240

5.  Antibodies attenuate the capacity of dendritic cells to stimulate HIV-specific cytotoxic T lymphocytes.

Authors:  Wilfried Posch; Sylvain Cardinaud; Chiraz Hamimi; Adam Fletcher; Annelies Mühlbacher; Klaus Loacker; Paul Eichberger; Manfred P Dierich; Gianfranco Pancino; Cornelia Lass-Flörl; Arnaud Moris; Asier Saez-Cirion; Doris Wilflingseder
Journal:  J Allergy Clin Immunol       Date:  2012-10-11       Impact factor: 10.793
  5 in total

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