Methods for simultaneous EEG-fMRI: an introductory review.

The simultaneous recording and analysis of electroencephalography (EEG) and fMRI data in human systems, cognitive and clinical neurosciences is rapidly evolving and has received substantial attention. The significance of multimodal brain imaging is documented by a steadily increasing number of laboratories now using simultaneous EEG-fMRI aiming to achieve both high temporal and spatial resolution of human brain function. Due to recent developments in technical and algorithmic instrumentation, the rate-limiting step in multimodal studies has shifted from data acquisition to analytic aspects. Here, we introduce and compare different methods for data integration and identify the benefits that come with each approach, guiding the reader toward an understanding and informed selection of the integration approach most suitable for addressing a particular research question.