| Literature DB >> 22552145 |
Justin D Lathia1, Jeremy N Rich.
Abstract
The attachment of stem cells to specialized functional niches instructs stem cell maintenance, with loss of adhesion associated with differentiation driven by cell-intrinsic programs. Id transcription factors are now shown to link cell-intrinsic maintenance programs and extrinsic cues by promoting adhesion of neural stem cells to the niche.Mesh:
Substances:
Year: 2012 PMID: 22552145 DOI: 10.1038/ncb2498
Source DB: PubMed Journal: Nat Cell Biol ISSN: 1465-7392 Impact factor: 28.824