| Literature DB >> 22551444 |
Arturo Orellana1, Sushil K Pandey, Sébastien Carret, Andrew E Greene, Jean-François Poisson.
Abstract
An efficient synthesis of (-)-kainic acid, through a high-pressure-promoted Diels-Alder cycloaddition of a vinylogous malonate derived from 4-hydroxyproline, is described. The bicyclic adduct could be converted into the natural product with complete stereocontrol.Entities:
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Year: 2012 PMID： 22551444 DOI： 10.1021/jo300608g
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354