| Literature DB >> 22550853 |
M V Pokrovskiĭ, T G Pokrovskaia, V V Gureev, A A Barsuk, E V Proskuriakova, M V Korokin, O S Gudyrev, A S Belous, V I Kochkarov, L M Danilenko, O V Levashova, N V Mal'tseva, O S Polianskaia.
Abstract
The ADMA-like pre-eclampsia in pregnant rats was modeled by daily introduction of L-NAME in a dose of 25 mg/kg for 7 days. L-arginine (200 mg/kg) prevented the development of arterial hypertension and a decrease in placentary microcirculation and microalbuminuria. The possibility of using L-arginine for the prevention of competitive eNOS inhibition by ADMA is discussed.Entities:
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Year: 2012 PMID： 22550853
Source DB: PubMed Journal: Eksp Klin Farmakol ISSN： 0869-2092