Literature DB >> 22549725

Sequence-specific synthesis of macromolecules using DNA-templated chemistry.

Phillip J Milnes1, Mireya L McKee, Jonathan Bath, Lijiang Song, Eugen Stulz, Andrew J Turberfield, Rachel K O'Reilly.   

Abstract

Using a strand exchange mechanism we have prepared, by DNA templated chemistry, two 10-mers with defined and tunable monomer sequences. An optimized reaction protocol achieves 85% coupling yield per step, demonstrating that DNA-templated chemistry is a powerful tool for the synthesis of macromolecules with full sequence control.

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Year:  2012        PMID: 22549725     DOI: 10.1039/c2cc31975f

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  8 in total

1.  Site-specific positioning of dendritic alkyl chains on DNA cages enables their geometry-dependent self-assembly.

Authors:  Thomas G W Edwardson; Karina M M Carneiro; Christopher K McLaughlin; Christopher J Serpell; Hanadi F Sleiman
Journal:  Nat Chem       Date:  2013-09-01       Impact factor: 24.427

2.  An autonomous molecular assembler for programmable chemical synthesis.

Authors:  Wenjing Meng; Richard A Muscat; Mireya L McKee; Phillip J Milnes; Afaf H El-Sagheer; Jonathan Bath; Benjamin G Davis; Tom Brown; Rachel K O'Reilly; Andrew J Turberfield
Journal:  Nat Chem       Date:  2016-04-11       Impact factor: 24.427

Review 3.  Functional DNA-Polymer Conjugates.

Authors:  Colette J Whitfield; Meizhou Zhang; Pia Winterwerber; Yuzhou Wu; David Y W Ng; Tanja Weil
Journal:  Chem Rev       Date:  2021-03-19       Impact factor: 60.622

4.  Coding and decoding libraries of sequence-defined functional copolymers synthesized via photoligation.

Authors:  Nicolas Zydziak; Waldemar Konrad; Florian Feist; Sergii Afonin; Steffen Weidner; Christopher Barner-Kowollik
Journal:  Nat Commun       Date:  2016-11-30       Impact factor: 14.919

5.  The Evolution of DNA-Templated Synthesis as a Tool for Materials Discovery.

Authors:  Rachel K O'Reilly; Andrew J Turberfield; Thomas R Wilks
Journal:  Acc Chem Res       Date:  2017-09-15       Impact factor: 22.384

6.  Reversibly Manipulating the Surface Chemistry of Polymeric Nanostructures via a "Grafting To" Approach Mediated by Nucleobase Interactions.

Authors:  Zan Hua; Robert Keogh; Zhen Li; Thomas R Wilks; Guosong Chen; Rachel K O'Reilly
Journal:  Macromolecules       Date:  2017-04-18       Impact factor: 5.985

7.  An Orthogonal Dynamic Covalent Chemistry Tool for Ring-Opening Polymerization of Cyclic Oligochalcogenides on Detachable Helical Peptide Templates.

Authors:  Quentin Laurent; Naomi Sakai; Stefan Matile
Journal:  Chemistry       Date:  2022-05-04       Impact factor: 5.020

8.  Synthesis of polymers with on-demand sequence structures via dually switchable and interconvertible polymerizations.

Authors:  Ze Zhang; Tian-You Zeng; Lei Xia; Chun-Yan Hong; De-Cheng Wu; Ye-Zi You
Journal:  Nat Commun       Date:  2018-07-03       Impact factor: 14.919

  8 in total

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