| Literature DB >> 22549725 |
Phillip J Milnes1, Mireya L McKee, Jonathan Bath, Lijiang Song, Eugen Stulz, Andrew J Turberfield, Rachel K O'Reilly.
Abstract
Using a strand exchange mechanism we have prepared, by DNA templated chemistry, two 10-mers with defined and tunable monomer sequences. An optimized reaction protocol achieves 85% coupling yield per step, demonstrating that DNA-templated chemistry is a powerful tool for the synthesis of macromolecules with full sequence control.Entities:
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Year: 2012 PMID: 22549725 DOI: 10.1039/c2cc31975f
Source DB: PubMed Journal: Chem Commun (Camb) ISSN: 1359-7345 Impact factor: 6.222