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Literature DB >> 22549435

Measurement of Haemophilus influenzae type a capsular polysaccharide antibodies in cord blood sera.

Daniel S Schmidt¹, Kathryn T Bieging, Patricia Gomez-de-León, Alberto Villaseñor-Sierra, Jaime Inostroza, John B Robbins, Rachel Schneerson, George M Carlone, Sandra Romero-Steiner.

Abstract

We measured anti-Haemophilus influenzae type a capsular polysaccharide serum immunoglobulin G antibodies in cord blood sera from Mexican (n = 68) and Chilean mothers (n = 72) by enzyme-linked immunosorbent assay. Measurable antibodies were found in 79.3% of samples. Immunoglobulin G antibodies correlated with serum bactericidal activity (r = 0.66). This enzyme-linked immunosorbent assay can be used for the evaluation of adaptive immune responses to Haemophilus influenzae type a and serosurveillance studies in populations at risk.

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Year: 2012 PMID： 22549435 PMCID： PMC3415859 DOI： 10.1097/INF.0b013e31825ab166

Source DB: PubMed Journal: Pediatr Infect Dis J ISSN： 0891-3668 Impact factor: 2.129

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