| Literature DB >> 22546505 |
Luc Pénicaud1, Sophie Meillon, Laurent Brondel.
Abstract
The discovery of leptin by Friedman and coll. in 1995 was a major step forward in our comprehensive view of energy homeostasis. Since the original paper, a tremendous amount of work has been performed in laboratories all over the world. Many recent reviews have described this work in details. In the present review, we focus on the role of leptin on food intake. It is accepted by most authors working in this field that the control of food intake can be divided in two closely-related system: the homeostatic system and the hedonic system. Leptin has been shown to act on both systems.Entities:
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Year: 2012 PMID: 22546505 DOI: 10.1016/j.biochi.2012.04.013
Source DB: PubMed Journal: Biochimie ISSN: 0300-9084 Impact factor: 4.079