BACKGROUND AND PURPOSE: Bronchiectasis causes pulmonary infections and loss of lung function, resulting in chronic respiratory symptoms and worsening health-related quality of life. The aims of this study were to measure symptoms of depression and anxiety in a sample of patients with bronchiectasis and evaluate their relationship to health outcomes and health-related quality of life. METHODS: This cross-sectional study included adolescents and adults with bronchiectasis. Patients completed the hospital anxiety and depression scale and the St. George respiratory questionnaire. Health outcome data, including clinical, radiological and spirometric values, were recorded from medical charts. RESULTS: Ninety-three participants with bronchiectasis of any aetiology were recruited: 20 % had elevated depression-related scores and 38 % had elevated anxiety-related scores. Increased symptoms of depression and anxiety were significantly associated with age; anxiety was associated with more frequent exacerbations. Regression analyses indicated that after controlling for demographic (gender and age) and clinical variables (exacerbations frequency, daily sputum, aetiology and spirometry), both depression and anxiety symptoms predicted significantly worse health-related quality of life. In comparison with other predictors, psychological symptoms explained the largest amount of variance in health-related quality of life. CONCLUSIONS: Symptoms of depression and anxiety were significant predictors of health-related quality of life in patients with bronchiectasis, independently of respiratory involvement, gender, age or other variables.
BACKGROUND AND PURPOSE:Bronchiectasis causes pulmonary infections and loss of lung function, resulting in chronic respiratory symptoms and worsening health-related quality of life. The aims of this study were to measure symptoms of depression and anxiety in a sample of patients with bronchiectasis and evaluate their relationship to health outcomes and health-related quality of life. METHODS: This cross-sectional study included adolescents and adults with bronchiectasis. Patients completed the hospital anxiety and depression scale and the St. George respiratory questionnaire. Health outcome data, including clinical, radiological and spirometric values, were recorded from medical charts. RESULTS: Ninety-three participants with bronchiectasis of any aetiology were recruited: 20 % had elevated depression-related scores and 38 % had elevated anxiety-related scores. Increased symptoms of depression and anxiety were significantly associated with age; anxiety was associated with more frequent exacerbations. Regression analyses indicated that after controlling for demographic (gender and age) and clinical variables (exacerbations frequency, daily sputum, aetiology and spirometry), both depression and anxiety symptoms predicted significantly worse health-related quality of life. In comparison with other predictors, psychological symptoms explained the largest amount of variance in health-related quality of life. CONCLUSIONS: Symptoms of depression and anxiety were significant predictors of health-related quality of life in patients with bronchiectasis, independently of respiratory involvement, gender, age or other variables.
Authors: J Roca; J Sanchis; A Agusti-Vidal; F Segarra; D Navajas; R Rodriguez-Roisin; P Casan; S Sans Journal: Bull Eur Physiopathol Respir Date: 1986 May-Jun
Authors: Janet Maurer; Venkata Rebbapragada; Soo Borson; Roger Goldstein; Mark E Kunik; Abebaw M Yohannes; Nicola A Hanania Journal: Chest Date: 2008-10 Impact factor: 9.410
Authors: Alexandra L Quittner; Michael S Schechter; Lawrence Rasouliyan; Tmirah Haselkorn; David J Pasta; Jeffrey S Wagener Journal: Chest Date: 2009-10-09 Impact factor: 9.410
Authors: David E Griffith; Jennifer Adjemian; Barbara A Brown-Elliott; Julie V Philley; D Rebecca Prevots; Christopher Gaston; Kenneth N Olivier; Richard J Wallace Journal: Am J Respir Crit Care Med Date: 2015-09-15 Impact factor: 21.405
Authors: Casilda Olveira; Gabriel Olveira; Francisco Espildora; Rosa-Maria Giron; Gerard Muñoz; Alexandra L Quittner; Miguel-Angel Martinez-Garcia Journal: Qual Life Res Date: 2013-10-19 Impact factor: 4.147
Authors: Marsus I Pumar; Mark Roll; Pamela Fung; Tricia A Rolls; James R Walsh; Rayleen V Bowman; Kwun M Fong; Ian A Yang Journal: J Thorac Dis Date: 2019-10 Impact factor: 2.895
Authors: Melissa J McDonnell; Stefano Aliberti; Pieter C Goeminne; Marcos I Restrepo; Simon Finch; Alberto Pesci; Lieven J Dupont; Thomas C Fardon; Robert Wilson; Michael R Loebinger; Dusan Skrbic; Dusanka Obradovic; Anthony De Soyza; Chris Ward; John G Laffey; Robert M Rutherford; James D Chalmers Journal: Lancet Respir Med Date: 2016-11-16 Impact factor: 30.700
Authors: Annemarie L Lee; Catherine J Hill; Nola Cecins; Sue Jenkins; Christine F McDonald; Angela T Burge; Linda Rautela; Robert G Stirling; Philip J Thompson; Anne E Holland Journal: Respir Res Date: 2014-04-15