| Literature DB >> 22543180 |
Benjamin Zmistowski1, Camilo Restrepo, Ronald Huang, William J Hozack, Javad Parvizi.
Abstract
Recent research has raised doubts regarding the utility of serum white blood cell count (WBC) for diagnosis of periprosthetic joint infection (PJI). As synovial WBC and neutrophil (PMN) percentage have been adopted as accurate markers of PJI, this study investigated the correlation of WBC in serum versus joint fluid and diagnostic value of all WBC levels for failed arthroplasty patients. 153 patients (73 PJI) undergoing revision knee arthroplasty were identified. Weak correlations between joint fluid and serum for WBC (R = 0.19), PMN count (R = 0.31), and lymphocyte count (R = -0.22) were observed. Diagnostic accuracy of PMN (93%) and WBC (93%) synovial count relative to serum was similar to synovial WBC (93%) and PMN% (95%) alone. Serum WBC analysis does little to improve the accurate diagnosis of PJI.Entities:
Mesh：
Year: 2012 PMID： 22543180 DOI： 10.1016/j.arth.2012.03.059
Source DB: PubMed Journal: J Arthroplasty ISSN： 0883-5403 Impact factor: 4.757