Literature DB >> 22540149

EUCAST technical note on Aspergillus and amphotericin B, itraconazole, and posaconazole.

M C Arendrup1, M Cuenca-Estrella, C Lass-Flörl, W W Hope.   

Abstract

The European Committee on Antimicrobial Susceptibility Testing Subcommittee on Antifungal Susceptibility Testing (EUCAST-AFST) has determined breakpoints for amphotericin B, itraconazole and posaconazole for Aspergillus species. This Technical Note is based on the EUCAST amphotericin B, itraconazole and posaconazole rationale documents (available on the EUCAST website: http://www.eucast.org/antifungal_susceptibility_testing_afst/rationale_documents_for_antifungals/). The amphotericin B and itraconazole breakpoints are based on epidemiological cut-off values and clinical experience. The posaconazole breakpoints are also based on pharmacokinetic and pharmacodynamic data. Breakpoints will be reviewed regularly or when new data emerge.
© 2012 The Authors. Clinical Microbiology and Infection © 2012 European Society of Clinical Microbiology and Infectious Diseases.

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Year:  2012        PMID： 22540149     DOI： 10.1111/j.1469-0691.2012.03890.x

Source DB:  PubMed          Journal:  Clin Microbiol Infect        ISSN： 1198-743X            Impact factor:   8.067


  54 in total

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10.  Determination of isavuconazole susceptibility of Aspergillus and Candida species by the EUCAST method.

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