Literature DB >> 22539720

Origins and genetic legacy of Neolithic farmers and hunter-gatherers in Europe.

Pontus Skoglund1, Helena Malmström, Maanasa Raghavan, Jan Storå, Per Hall, Eske Willerslev, M Thomas P Gilbert, Anders Götherström, Mattias Jakobsson.   

Abstract

The farming way of life originated in the Near East some 11,000 years ago and had reached most of the European continent 5000 years later. However, the impact of the agricultural revolution on demography and patterns of genomic variation in Europe remains unknown. We obtained 249 million base pairs of genomic DNA from ~5000-year-old remains of three hunter-gatherers and one farmer excavated in Scandinavia and find that the farmer is genetically most similar to extant southern Europeans, contrasting sharply to the hunter-gatherers, whose distinct genetic signature is most similar to that of extant northern Europeans. Our results suggest that migration from southern Europe catalyzed the spread of agriculture and that admixture in the wake of this expansion eventually shaped the genomic landscape of modern-day Europe.

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Year:  2012        PMID: 22539720     DOI: 10.1126/science.1216304

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  182 in total

1.  Deep History of East Asian Populations Revealed Through Genetic Analysis of the Ainu.

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Journal:  Genetics       Date:  2015-10-23       Impact factor: 4.562

2.  Neolithic and Bronze Age migration to Ireland and establishment of the insular Atlantic genome.

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Journal:  Proc Natl Acad Sci U S A       Date:  2015-12-28       Impact factor: 11.205

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4.  The characteristic trajectory of a fixing allele: a consequence of fictitious selection that arises from conditioning.

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Journal:  Genetics       Date:  2013-09-03       Impact factor: 4.562

5.  Ancient DNA and human history.

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6.  Cultural evolutionary theory: How culture evolves and why it matters.

Authors:  Nicole Creanza; Oren Kolodny; Marcus W Feldman
Journal:  Proc Natl Acad Sci U S A       Date:  2017-07-24       Impact factor: 11.205

7.  Ancient mitochondrial DNA from the northern fringe of the Neolithic farming expansion in Europe sheds light on the dispersion process.

Authors:  Helena Malmström; Anna Linderholm; Pontus Skoglund; Jan Storå; Per Sjödin; M Thomas P Gilbert; Gunilla Holmlund; Eske Willerslev; Mattias Jakobsson; Kerstin Lidén; Anders Götherström
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2015-01-19       Impact factor: 6.237

Review 8.  Recent advances in the study of fine-scale population structure in humans.

Authors:  John Novembre; Benjamin M Peter
Journal:  Curr Opin Genet Dev       Date:  2016-09-20       Impact factor: 5.578

9.  Separating endogenous ancient DNA from modern day contamination in a Siberian Neandertal.

Authors:  Pontus Skoglund; Bernd H Northoff; Michael V Shunkov; Anatoli P Derevianko; Svante Pääbo; Johannes Krause; Mattias Jakobsson
Journal:  Proc Natl Acad Sci U S A       Date:  2014-01-27       Impact factor: 11.205

10.  Neolithic mitochondrial haplogroup H genomes and the genetic origins of Europeans.

Authors:  Paul Brotherton; Wolfgang Haak; Jennifer Templeton; Guido Brandt; Julien Soubrier; Christina Jane Adler; Stephen M Richards; Clio Der Sarkissian; Robert Ganslmeier; Susanne Friederich; Veit Dresely; Mannis van Oven; Rosalie Kenyon; Mark B Van der Hoek; Jonas Korlach; Khai Luong; Simon Y W Ho; Lluis Quintana-Murci; Doron M Behar; Harald Meller; Kurt W Alt; Alan Cooper
Journal:  Nat Commun       Date:  2013       Impact factor: 14.919

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