| Literature DB >> 22537629 |
Christian Holmberg1, Olaf Nielsen.
Abstract
Correct regulation of DNA nucleotide biosynthesis is emerging as a key issue of importance for genome integrity. The fission yeast Spd1 protein can modulate the activity of ribonucleotide reductase (RNR) by at least three different mechanisms. Now a paper reports that Spd1 turnover is linked to ongoing DNA synthesis.Entities:
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Year: 2012 PMID： 22537629 DOI： 10.1016/j.cub.2012.03.019
Source DB: PubMed Journal: Curr Biol ISSN： 0960-9822 Impact factor: 10.834