BACKGROUND: Cardiac paragangliomas are an extremely rare subset of chromaffin cell tumors that develop from neural crest cells. METHODS: Between March 2004 and October 2010, 7 male patients from our two institutions who underwent surgical resection of cardiac paraganglioma were retrospectively reviewed. RESULTS: In 5 patients, paragangliomas originated from the roof of the left atrium, and in 2 patients, they originated from the aortic root. Hospital mortality was 14%. CONCLUSIONS: Complete surgical resection remains the mainstay of therapy and can be curative, but carries a significant risk of intraoperative bleeding and usually requires cardiopulmonary bypass and often complex resection techniques, including cardiac autotransplantation.
BACKGROUND:Cardiac paragangliomas are an extremely rare subset of chromaffin cell tumors that develop from neural crest cells. METHODS: Between March 2004 and October 2010, 7 male patients from our two institutions who underwent surgical resection of cardiac paraganglioma were retrospectively reviewed. RESULTS: In 5 patients, paragangliomas originated from the roof of the left atrium, and in 2 patients, they originated from the aortic root. Hospital mortality was 14%. CONCLUSIONS: Complete surgical resection remains the mainstay of therapy and can be curative, but carries a significant risk of intraoperative bleeding and usually requires cardiopulmonary bypass and often complex resection techniques, including cardiac autotransplantation.
Authors: Carlos A Hinojosa; Hugo Laparra-Escareno; Javier E Anaya-Ayala; Rene Lizola; Adriana Torres-Machorro; Armando Gamboa-Domínguez Journal: Tex Heart Inst J Date: 2017-02-01
Authors: Brandon A Guenthart; Winston Trope; Worasak Keeyapaj; Julianna J Weiel; Amanda Edmonson; John W MacArthur; Justin P Annes; Y Joseph Woo; Natalie S Lui Journal: Gen Thorac Cardiovasc Surg Date: 2020-10-19