Juan Du1, Lei Wang, Jianjun Han, Lifen Gao, Chunhong Ma, Xiaohong Liang. 1. Key Laboratory for Experimental Teratology of Ministry of Education and Institute of Immunology, Shandong University School of Medicine, 44 Wenhua Xi Road, Jinan 250012, PR China.
Abstract
OBJECTIVES: To measure the levels of serum soluble death receptor 5 (sDR5) in patients with hepatitis B. DESIGN AND METHODS: sDR5 concentration in 60 HBV infected patients and 30 healthy volunteers were measured by ELISA. RESULTS: sDR5 concentration in the HBV infected patients was decreased and correlated with serum ALT, Tbil level, albumin/globulin ratio and HBV antigen level. CONCLUSIONS: Decreased serum sDR5 is associated with high level of liver damage and inhibited HBV antigen expression.
OBJECTIVES: To measure the levels of serum soluble death receptor 5 (sDR5) in patients with hepatitis B. DESIGN AND METHODS: sDR5 concentration in 60 HBV infectedpatients and 30 healthy volunteers were measured by ELISA. RESULTS: sDR5 concentration in the HBV infectedpatients was decreased and correlated with serum ALT, Tbil level, albumin/globulin ratio and HBV antigen level. CONCLUSIONS: Decreased serum sDR5 is associated with high level of liver damage and inhibited HBV antigen expression.