Literature DB >> 22535916

Histopathological and postoperative behavioral comparison of rodent oral tongue resection: fiber-enabled CO2 laser versus electrocautery.

Courtney B Shires1, Jennifer M Saputra, Lauren King, Jerome W Thompson, Detlef H Heck, Merry E Sebelik, John D Boughter.   

Abstract

OBJECTIVE: To compare operative time and hemostasis of fiber-enabled CO(2) laser (FECL) energy to that of the electrocautery (EC) technique for oral tongue resection, to compare return to oral intake and preoperative weight after FECL and EC resection, and to compare histologic changes in adjacent tissue after FECL and EC resection. STUDY
DESIGN: Prospective animal study.
SETTING: Research laboratory. SUBJECTS AND METHODS: The CO(2) laser fiber and the Bovie cautery were each used to resect the anterior tongue in 15 adult rats. Fixative perfusion and killing were performed on postoperative day 0 (n = 10), 3 (n = 10), or 7 (n = 10). Body weight, food intake, and water intake were recorded daily for 3- and 7-day survival rats. After preparation for histologic analysis, the tongue tissue was graded with a mucosal wound-healing scale (MWHS).
RESULTS: A higher incidence of intraoperative bleeding and shorter operative times were noted in the EC group. No statistically significant difference in postoperative food or water intake between the EC and FECL groups was noted. The FECL group returned to baseline weight by postoperative day 6. MWHS scores were lower in the EC group by postoperative day 3 and lower in the FECL group by postoperative day 7.
CONCLUSIONS: Both EC and FECL are effective for resection of the tongue in rats. EC has the advantage of shorter operative time and lower MWHS scores by postoperative day 3; FECL has the advantages of less intraoperative bleeding, faster return to baseline body weight, and lower MWHS score by postoperative day 7.

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Year:  2012        PMID: 22535916      PMCID: PMC4441337          DOI: 10.1177/0194599812445559

Source DB:  PubMed          Journal:  Otolaryngol Head Neck Surg        ISSN: 0194-5998            Impact factor:   3.497


  10 in total

1.  Laser surgery in otolaryngology: interaction of CO2 laser and soft tissue.

Authors:  S Mihashi; G J Jako; J Incze; M S Strong; C W Vaughan
Journal:  Ann N Y Acad Sci       Date:  1976-01-30       Impact factor: 5.691

2.  Microdebrider vs electrocautery: a comparison of tonsillar wound healing histopathology in a canine model.

Authors:  Kaalan Johnson; Andrew Vaughan; Craig Derkay; J Camille Welch; Alice Werner; M Ann Kuhn; Sylvia Singletary; Peter Bondy
Journal:  Otolaryngol Head Neck Surg       Date:  2008-04       Impact factor: 3.497

3.  A review of carbon dioxide laser surgery in the oral cavity and pharynx.

Authors:  P H Rhys Evans; J W Frame; J Brandrick
Journal:  J Laryngol Otol       Date:  1986-01       Impact factor: 1.469

4.  Lasers for otosclerosis: CO2 vs. Argon and KTP-532.

Authors:  S G Lesinski; A Palmer
Journal:  Laryngoscope       Date:  1989-06       Impact factor: 3.325

5.  Laser surgery of the vocal cords. An experimental study with carbon dioxide lasers on dogs.

Authors:  G J Jako
Journal:  Laryngoscope       Date:  1972-12       Impact factor: 3.325

6.  Resection of the tongue with the carbon dioxide laser.

Authors:  J A Carruth
Journal:  J Laryngol Otol       Date:  1982-06       Impact factor: 1.469

7.  Effects of scalpel, electrocautery, and CO2 and KTP lasers on wound healing in rat tongues.

Authors:  J F Carew; R F Ward; A LaBruna; P A Torzilli; W S Schley
Journal:  Laryngoscope       Date:  1998-03       Impact factor: 3.325

8.  Transoral management of localized carcinoma of the oral cavity using the CO2 laser.

Authors:  M S Strong; C W Vaughan; G B Healy; S M Shapshay; G J Jako
Journal:  Laryngoscope       Date:  1979-06       Impact factor: 3.325

9.  Soft tissue effects of the THC:YAG laser on canine vocal cords.

Authors:  S L Kay; M C Oz; M Haber; A Blitzer; M R Treat; S L Trokel
Journal:  Otolaryngol Head Neck Surg       Date:  1992-09       Impact factor: 3.497

10.  Remodeling of the rat gingiva induced by CO2 laser coagulation mode.

Authors:  Akira Yamasaki; Kiyoharu Tamamura; Yuuko Sakurai; Noriko Okuyama; Junko Yusa; Hiroshi Ito
Journal:  Lasers Surg Med       Date:  2008-12       Impact factor: 4.025

  10 in total
  3 in total

1.  Epithelial separation theory for post-tonsillectomy secondary hemorrhage: evidence in a mouse model and potential heparin-binding epidermal growth factor-like growth factor therapy.

Authors:  Daniel M Beswick; Chloe Santa Maria; Noel F Ayoub; Robson Capasso; Peter Luke Santa Maria
Journal:  Eur Arch Otorhinolaryngol       Date:  2017-11-29       Impact factor: 2.503

Review 2.  Application of laser in oral surgery.

Authors:  Mohammad Asnaashari; Saeede Zadsirjan
Journal:  J Lasers Med Sci       Date:  2014

3.  Fire ignition during laser surgery in pet rodents.

Authors:  Tommaso Collarile; Nicola Di Girolamo; Giordano Nardini; Ivano Antonio Ciraci; Paolo Selleri
Journal:  BMC Vet Res       Date:  2012-09-26       Impact factor: 2.741

  3 in total

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