Literature DB >> 22535058

Dynamic spectroscopic phase microscopy for quantifying hemoglobin concentration and dynamic membrane fluctuation in red blood cells.

Yunhun Jang1, Jaeduck Jang, YongKeun Park.   

Abstract

We report a technique for simultaneous label-free quantification of cytoplasmic hemoglobin Hb concentration and dynamic membrane fluctuation in individual red blood cells (RBCs). Spectroscopic phase microscopy equipped with three different coherent laser sources and a color detector records three wavelength-dependent quantitative phase images in a single shot of a color-coded hologram. Using molecular specific dispersion, we demonstrate the extraction of Hb concentration and the dynamic membrane fluctuation from individual RBCs.
© 2012 Optical Society of America

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Year:  2012        PMID: 22535058     DOI: 10.1364/OE.20.009673

Source DB:  PubMed          Journal:  Opt Express        ISSN: 1094-4087            Impact factor:   3.894


  18 in total

1.  Label-free characterization of white blood cells by measuring 3D refractive index maps.

Authors:  Jonghee Yoon; Kyoohyun Kim; HyunJoo Park; Chulhee Choi; Seongsoo Jang; YongKeun Park
Journal:  Biomed Opt Express       Date:  2015-09-09       Impact factor: 3.732

Review 2.  Review of quantitative phase-digital holographic microscopy: promising novel imaging technique to resolve neuronal network activity and identify cellular biomarkers of psychiatric disorders.

Authors:  Pierre Marquet; Christian Depeursinge; Pierre J Magistretti
Journal:  Neurophotonics       Date:  2014-09-22       Impact factor: 3.593

3.  Multi-wavelength quantitative polarization and phase microscope.

Authors:  Xiaobo Tian; Xingzhou Tu; Kimiko Della Croce; Guang Yao; Haijiang Cai; Neal Brock; Stanley Pau; Rongguang Liang
Journal:  Biomed Opt Express       Date:  2019-03-05       Impact factor: 3.732

4.  Erythrocyte volumetric measurements in imaging flow cytometry using simultaneous three-wavelength digital holographic microscopy.

Authors:  Nir A Turko; Natan T Shaked
Journal:  Biomed Opt Express       Date:  2020-10-22       Impact factor: 3.732

5.  Holotomography: Refractive Index as an Intrinsic Imaging Contrast for 3-D Label-Free Live Cell Imaging.

Authors:  Doyeon Kim; Sangyun Lee; Moosung Lee; Juntaek Oh; Su-A Yang; YongKeun Park
Journal:  Adv Exp Med Biol       Date:  2021       Impact factor: 2.622

6.  Single-shot dual-wavelength interferometric microscopy.

Authors:  Poorya Hosseini; Di Jin; Zahid Yaqoob; Peter T C So
Journal:  Methods       Date:  2017-10-25       Impact factor: 3.608

7.  High-resolution three-dimensional imaging of red blood cells parasitized by Plasmodium falciparum and in situ hemozoin crystals using optical diffraction tomography.

Authors:  Kyoohyun Kim; HyeOk Yoon; Monica Diez-Silva; Ming Dao; Ramachandra R Dasari; YongKeun Park
Journal:  J Biomed Opt       Date:  2014-01       Impact factor: 3.170

8.  Diffraction optical tomography using a quantitative phase imaging unit.

Authors:  Kyoohyun Kim; Zahid Yaqoob; KyeoReh Lee; Jeon Woong Kang; Youngwoon Choi; Poorya Hosseini; Peter T C So; YongKeun Park
Journal:  Opt Lett       Date:  2014-12-15       Impact factor: 3.776

9.  Quantitative phase imaging techniques for the study of cell pathophysiology: from principles to applications.

Authors:  KyeoReh Lee; Kyoohyun Kim; Jaehwang Jung; JiHan Heo; Sangyeon Cho; Sangyun Lee; Gyuyoung Chang; YoungJu Jo; Hyunjoo Park; YongKeun Park
Journal:  Sensors (Basel)       Date:  2013-03-28       Impact factor: 3.576

10.  Intracellular water exchange for measuring the dry mass, water mass and changes in chemical composition of living cells.

Authors:  Francisco Feijó Delgado; Nathan Cermak; Vivian C Hecht; Sungmin Son; Yingzhong Li; Scott M Knudsen; Selim Olcum; John M Higgins; Jianzhu Chen; William H Grover; Scott R Manalis
Journal:  PLoS One       Date:  2013-07-02       Impact factor: 3.240

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