BACKGROUND/AIMS: It is not sufficiently clear whether the continued good outcomes obtained with laparoscopic Nissen operation after a short follow-up will continue after several years. The aim of our re-search was to make a comparative analysis of the quality of life and presence of symptoms 5 and 10 years after surgery. METHODOLOGY: 123 cases (69 men and 74 women) average age of 49.78 years (+12.13) were studied with average follow-up of 10.15 years. The quality of life was assessed based on a personal modified Gigli questionnaire with 32 items. RESULTS: The overall analysis revealed that the levels of quality of life decreased from 2006 (74.72) to 2011 (70.04) but remain significantly higher than those recorded prior to surgery (57.28). Of the 123 cases, 115 were satisfied with the surgery (93.5%) and 8 were not (6.5%);of the latter, six were undergoing antidepressant treatment. In 4 cases it was necessary to re-operate, 1 for dysphagia and 3 due to relapse. CONCLUSIONS: Al-though the results recorded in 2011 are slightly lower than those obtained in 2006, they remain well above those recorded before surgery. Therefore, the laparoscopic Nissen operation continues to be an excellent operation in the treatment of GERD
BACKGROUND/AIMS: It is not sufficiently clear whether the continued good outcomes obtained with laparoscopic Nissen operation after a short follow-up will continue after several years. The aim of our re-search was to make a comparative analysis of the quality of life and presence of symptoms 5 and 10 years after surgery. METHODOLOGY: 123 cases (69 men and 74 women) average age of 49.78 years (+12.13) were studied with average follow-up of 10.15 years. The quality of life was assessed based on a personal modified Gigli questionnaire with 32 items. RESULTS: The overall analysis revealed that the levels of quality of life decreased from 2006 (74.72) to 2011 (70.04) but remain significantly higher than those recorded prior to surgery (57.28). Of the 123 cases, 115 were satisfied with the surgery (93.5%) and 8 were not (6.5%);of the latter, six were undergoing antidepressant treatment. In 4 cases it was necessary to re-operate, 1 for dysphagia and 3 due to relapse. CONCLUSIONS: Al-though the results recorded in 2011 are slightly lower than those obtained in 2006, they remain well above those recorded before surgery. Therefore, the laparoscopic Nissen operation continues to be an excellent operation in the treatment of GERD