Literature DB >> 22534313

Severe adalimumab-induced thrombocytopenia in a patient with Crohn's disease.

M J Casanova1, M Chaparro, S Martínez, I Vicuña, J P Gisbert.   

Abstract

Crohn's disease is a chronic transmural inflammatory disorder characterized by inflammation of the intestine. Anti-TNF-α drugs are used for induction and maintenance of remission in patients with this condition. Thrombocytopenia is an uncommon side effect of treatment with anti-TNF-α drugs. We report the case of a 71-year-old woman diagnosed with Crohn's disease who developed severe adalimumab-induced thrombocytopenia and who did not respond to standard therapy for thrombocytopenia.
© 2012 European Crohn's and Colitis Organisation. Published by Elsevier B.V. All rights reserved.

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Year:  2012        PMID: 22534313     DOI: 10.1016/j.crohns.2012.04.001

Source DB:  PubMed          Journal:  J Crohns Colitis        ISSN: 1873-9946            Impact factor:   9.071


  4 in total

Review 1.  Hematologic side effects of biologics and kinase inhibitors used in rheumatologic diseases: a review of the current evidence.

Authors:  Sambhawana Bhandari; Maun Ranjan Baral; Matthew Barbery; Alla Rudinskaya; Oleg Sostin
Journal:  Ann Hematol       Date:  2022-06-27       Impact factor: 4.030

2.  Associations of Platelet Count with Inflammation and Response to Anti-TNF-α Therapy in Patients with Ankylosing Spondylitis.

Authors:  Hongyan Qian; Rongjuan Chen; Bin Wang; Xiaoqing Yuan; Shiju Chen; Yuan Liu; Guixiu Shi
Journal:  Front Pharmacol       Date:  2020-11-06       Impact factor: 5.810

3.  Adalimumab as a potential cause of drug-induced thrombocytopaenic microangiopathy.

Authors:  Lorenzo Falsetti; Mattia Sampaolesi; Francesca Riccomi; Cinzia Nitti
Journal:  BMJ Case Rep       Date:  2020-03-04

4.  Adalimumab-Induced Thrombocytopenia in a Patient With Hidradenitis Suppurativa.

Authors:  Amna Al-Tkrit; Zaid Obada; Sara Muqeet; Jose Cervantes
Journal:  Cureus       Date:  2021-04-30
  4 in total

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