Literature DB >> 22532684

Comparison of the host immune response to herpes simplex virus 1 (HSV-1) and HSV-2 at two different mucosal sites.

Min Zheng1, Christopher D Conrady, Julie M Ward, Katie M Bryant-Hudson, Daniel J J Carr.   

Abstract

A study was undertaken to compare the host immune responses to herpes simplex virus 1 (HSV-1) and HSV-2 infection by the ocular or genital route in mice. Titers of HSV-2 from tissue samples were elevated regardless of the route of infection. The elevation in titers of HSV-2, including cell infiltration and cytokine/chemokine levels in the central nervous system relative to those found following HSV-1 infection, was correlative with inflammation. These results underscore a dichotomy between the host immune responses to closely related alphaherpesviruses.

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Year:  2012        PMID： 22532684      PMCID： PMC3416341          DOI： 10.1128/JVI.00702-12

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  40 in total

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Journal:  J Virol       Date:  2011-01-26       Impact factor: 5.103

2.  Control of the central chemoreflex by A5 noradrenergic neurons in rats.

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Journal:  N Engl J Med       Date:  2012-01-05       Impact factor: 91.245

4.  The application of a plasmid DNA encoding IFN-alpha 1 postinfection enhances cumulative survival of herpes simplex virus type 2 vaginally infected mice.

Authors:  P Härle; S Noisakran; D J Carr
Journal:  J Immunol       Date:  2001-02-01       Impact factor: 5.422

5.  Differential roles of B cells and IFN-gamma-secreting CD4(+) T cells in innate and adaptive immune control of genital herpes simplex virus type 2 infection in mice.

Authors:  Ali M Harandi; Bo Svennerholm; Jan Holmgren; Kristina Eriksson
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6.  Using centralized laboratory data to monitor trends in herpes simplex virus type 1 and 2 infection in British Columbia and the changing etiology of genital herpes.

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7.  Herpes simplex virus virion host shutoff (vhs) activity alters periocular disease in mice.

Authors:  T J Smith; C E Ackland-Berglund; D A Leib
Journal:  J Virol       Date:  2000-04       Impact factor: 5.103

8.  A5-positive primary sensory neurons are nonpermissive for productive infection with herpes simplex virus 1 in vitro.

Authors:  Andrea S Bertke; Sophia M Swanson; Jenny Chen; Yumi Imai; Paul R Kinchington; Todd P Margolis
Journal:  J Virol       Date:  2011-04-20       Impact factor: 5.103

9.  A live-attenuated HSV-2 ICP0 virus elicits 10 to 100 times greater protection against genital herpes than a glycoprotein D subunit vaccine.

Authors:  William P Halford; Ringo Püschel; Edward Gershburg; Andrew Wilber; Svetlana Gershburg; Brandon Rakowski
Journal:  PLoS One       Date:  2011-03-11       Impact factor: 3.240

10.  Glycoprotein-D-adjuvant vaccine to prevent genital herpes.

Authors:  Lawrence R Stanberry; Spotswood L Spruance; Anthony L Cunningham; David I Bernstein; Adrian Mindel; Stephen Sacks; Stephen Tyring; Fred Y Aoki; Moncef Slaoui; Martine Denis; Pierre Vandepapeliere; Gary Dubin
Journal:  N Engl J Med       Date:  2002-11-21       Impact factor: 91.245
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  7 in total

1.  Regulation of Herpes Simplex Virus Glycoprotein-Induced Cascade of Events Governing Cell-Cell Fusion.

Authors:  Doina Atanasiu; Wan Ting Saw; Roselyn J Eisenberg; Gary H Cohen
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2.  T cell response kinetics determines neuroinfection outcomes during murine HSV infection.

Authors:  Aisha G Lee; Jason M Scott; Maria Rita Fabbrizi; Xiaoping Jiang; Dorothy K Sojka; Mark J Miller; Megan T Baldridge; Wayne M Yokoyama; Haina Shin
Journal:  JCI Insight       Date:  2020-03-12

3.  Role of immediate early protein ICP27 in the differential sensitivity of herpes simplex viruses 1 and 2 to leptomycin B.

Authors:  Donglim Park; Joy Lengyel; Stephen A Rice
Journal:  J Virol       Date:  2013-06-05       Impact factor: 5.103

4.  HSV-1 strain McKrae is more neuroinvasive than HSV-1 KOS after corneal or vaginal inoculation in mice.

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Journal:  Virus Res       Date:  2013-01-20       Impact factor: 3.303

Review 5.  Mucosal herpes immunity and immunopathology to ocular and genital herpes simplex virus infections.

Authors:  Aziz Alami Chentoufi; Lbachir Benmohamed
Journal:  Clin Dev Immunol       Date:  2012-12-24

6.  Herpes simplex virus serotype and entry receptor availability alter CNS disease in a mouse model of neonatal HSV.

Authors:  Sarah J Kopp; Hantamalala R Ranaivo; Douglas R Wilcox; Andrew H Karaba; Mark S Wainwright; William J Muller
Journal:  Pediatr Res       Date:  2014-09-08       Impact factor: 3.756

7.  Global Gene Expression Analysis of the Brainstem in EV71- and CVA16-Infected Gerbils.

Authors:  Yi-Sheng Sun; Zhang-Nv Yang; Fang Xu; Chen Chen; Hang-Jing Lu; Jian-Min Jiang; Yan-Jun Zhang; Han-Ping Zhu; Ping-Ping Yao
Journal:  Viruses       Date:  2019-12-30       Impact factor: 5.048
  7 in total

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