Literature DB >> 22531758

Establishment, retention, and loss to follow-up in outpatient HIV care.

John A Fleishman1, Baligh R Yehia, Richard D Moore, P Todd Korthuis, Kelly A Gebo.   

Abstract

BACKGROUND: For optimal clinical benefit, HIV-infected patients should receive periodic outpatient care indefinitely. However, initially establishing HIV care and subsequent retention in care are problematic. This study examines establishment, retention, and loss to follow-up (LTFU) in a large multi-site cohort over a 2-8 year period.
METHODS: Medical record data were reviewed for 22,984 adult HIV patients receiving care at 12 clinics in the HIV Research Network between 2001 and 2009. Three dichotomous outcome measures were based on each patient's history of outpatient visits. Establishment reflects whether the patient made outpatient visits for longer than 6 months after initial enrollment. The retention measure reflects whether the patient had at least 2 outpatient visits separated by 90 days in each year in care. LTFU reflects whether the patient had no outpatient visits for more than 12 months without returning. Multiple logistic regression examined demographic and clinical correlates of each outcome and the combined outcome of meeting all 3 measures.
RESULTS: Overall, 21.7% of patients never established HIV care after an initial visit. Among established patients, 57.4% did not meet the retention criterion in all years, and 34.9% were LTFU. Only 20.4% of all patients met all 3 criteria. The odds of successfully meeting all 3 criteria were higher for women, for older patients, for Hispanics compared with whites, and for those with CD4 levels ≤50 cells per cubic millimeter.
CONCLUSIONS: These data highlight the need to improve establishment and retention in HIV care.

Entities:  

Mesh:

Year:  2012        PMID: 22531758      PMCID: PMC3383913          DOI: 10.1097/QAI.0b013e318258c696

Source DB:  PubMed          Journal:  J Acquir Immune Defic Syndr        ISSN: 1525-4135            Impact factor:   3.731


  32 in total

1.  Nonadherence to medical appointments is associated with increased plasma HIV RNA and decreased CD4 cell counts in a community-based HIV primary care clinic.

Authors:  M B Berg; S A Safren; M J Mimiaga; C Grasso; S Boswell; K H Mayer
Journal:  AIDS Care       Date:  2005-10

2.  Predictors identified for losses to follow-up among HIV-seropositive patients.

Authors:  Emilie Lanoy; Murielle Mary-Krause; Pierre Tattevin; Rosemary Dray-Spira; Claudine Duvivier; Patricia Fischer; Yolande Obadia; France Lert; Dominique Costagliola
Journal:  J Clin Epidemiol       Date:  2006-05-30       Impact factor: 6.437

3.  Factors associated with the failure of HIV-positive persons to return for scheduled medical visits.

Authors:  Claudio Arici; Diego Ripamonti; Franco Maggiolo; Marco Rizzi; Maria Grazia Finazzi; Patrizio Pezzotti; Fredy Suter
Journal:  HIV Clin Trials       Date:  2002 Jan-Feb

4.  Predictors of outpatient medical appointment attendance among persons with HIV.

Authors:  S L Catz; J B McClure; G N Jones; P J Brantley
Journal:  AIDS Care       Date:  1999-06

5.  Highly active antiretroviral therapy in a large urban clinic: risk factors for virologic failure and adverse drug reactions.

Authors:  G M Lucas; R E Chaisson; R D Moore
Journal:  Ann Intern Med       Date:  1999-07-20       Impact factor: 25.391

6.  Patients referred to an urban HIV clinic frequently fail to establish care: factors predicting failure.

Authors:  Thomas P Giordano; Fehmida Visnegarwala; A Clinton White; Catherine L Troisi; Ralph F Frankowski; Christine M Hartman; Richard M Grimes
Journal:  AIDS Care       Date:  2005-08

7.  Efficacy of a brief case management intervention to link recently diagnosed HIV-infected persons to care.

Authors:  Lytt I Gardner; Lisa R Metsch; Pamela Anderson-Mahoney; Anita M Loughlin; Carlos del Rio; Steffanie Strathdee; Stephanie L Sansom; Harvey A Siegal; Alan E Greenberg; Scott D Holmberg
Journal:  AIDS       Date:  2005-03-04       Impact factor: 4.177

8.  Retention in care: a challenge to survival with HIV infection.

Authors:  Thomas P Giordano; Allen L Gifford; A Clinton White; Maria E Suarez-Almazor; Linda Rabeneck; Christine Hartman; Lisa I Backus; Larry A Mole; Robert O Morgan
Journal:  Clin Infect Dis       Date:  2007-04-23       Impact factor: 9.079

9.  Discontinuation from HIV medical care: squandering treatment opportunities.

Authors:  Jeffrey H Samet; Kenneth A Freedberg; Jacqueline B Savetsky; Lisa M Sullivan; Latha Padmanabhan; Michael D Stein
Journal:  J Health Care Poor Underserved       Date:  2003-05

10.  Association between adherence to antiretroviral therapy and human immunodeficiency virus drug resistance.

Authors:  Ajay K Sethi; David D Celentano; Stephen J Gange; Richard D Moore; Joel E Gallant
Journal:  Clin Infect Dis       Date:  2003-09-19       Impact factor: 9.079

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  96 in total

1.  Factors affecting linkage to care and engagement in care for newly diagnosed HIV-positive adolescents within fifteen adolescent medicine clinics in the United States.

Authors:  Morgan M Philbin; Amanda E Tanner; Anna DuVal; Jonathan M Ellen; Jiahong Xu; Bill Kapogiannis; Jim Bethel; J Dennis Fortenberry
Journal:  AIDS Behav       Date:  2014-08

2.  Antiretroviral Refill Adherence Correlates with, But Poorly Predicts Retention in HIV Care.

Authors:  Robert A Bonacci; Katherine Frasca; Lyles Swift; Daohang Sha; Warren B Bilker; Laura Bamford; Baligh R Yehia; Robert Gross
Journal:  AIDS Behav       Date:  2016-05

3.  Comparison of HIV outcomes for patients linked at hospital versus community-based clinics.

Authors:  Asher J Schranz; Kathleen A Brady; Florence Momplaisir; Joshua P Metlay; Alisa Stephens; Baligh R Yehia
Journal:  AIDS Patient Care STDS       Date:  2015-02-09       Impact factor: 5.078

4.  Comparing Different Measures of Retention in Care Among a Cohort of Adolescents and Young Adults Living with Behaviorally-Acquired HIV.

Authors:  Caitlin S Sayegh; Sarah M Wood; Marvin Belzer; Nadia L Dowshen
Journal:  AIDS Behav       Date:  2020-01

5.  Lost to follow-up: failure to engage children in care in the first three months of diagnosis.

Authors:  Edwin Masese Machine; Susan L Gillespie; Nuria Homedes; Beatrice J Selwyn; Michael W Ross; Gabriel Anabwani; Gordon Schutze; Mark W Kline
Journal:  AIDS Care       Date:  2016-05-10

6.  Behind the cascade: analyzing spatial patterns along the HIV care continuum.

Authors:  Michael G Eberhart; Baligh R Yehia; Amy Hillier; Chelsea D Voytek; Michael B Blank; Ian Frank; David S Metzger; Kathleen A Brady
Journal:  J Acquir Immune Defic Syndr       Date:  2013-11-01       Impact factor: 3.731

7.  Hospitalization rates of people living with HIV in the United States, 2009.

Authors:  Marcus A Bachhuber; William N Southern
Journal:  Public Health Rep       Date:  2014 Mar-Apr       Impact factor: 2.792

8.  Laboratory Measures as Proxies for Primary Care Encounters: Implications for Quantifying Clinical Retention Among HIV-Infected Adults in North America.

Authors:  Peter F Rebeiro; Keri N Althoff; Bryan Lau; John Gill; Alison G Abraham; Michael A Horberg; Mari M Kitahata; Baligh R Yehia; Hasina Samji; John T Brooks; Kate Buchacz; Sonia Napravnik; Michael J Silverberg; Anita Rachlis; Kelly A Gebo; Timothy R Sterling; Richard D Moore; Stephen J Gange
Journal:  Am J Epidemiol       Date:  2015-11-17       Impact factor: 4.897

9.  Accuracy of definitions for linkage to care in persons living with HIV.

Authors:  Sara C Keller; Baligh R Yehia; Michael G Eberhart; Kathleen A Brady
Journal:  J Acquir Immune Defic Syndr       Date:  2013-08-15       Impact factor: 3.731

10.  The Cost-effectiveness and Budget Impact of 2-Drug Dolutegravir-Lamivudine Regimens for the Treatment of HIV Infection in the United States.

Authors:  Michael P Girouard; Paul E Sax; Robert A Parker; Babafemi Taiwo; Kenneth A Freedberg; Roy M Gulick; Milton C Weinstein; A David Paltiel; Rochelle P Walensky
Journal:  Clin Infect Dis       Date:  2015-12-09       Impact factor: 9.079

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