Literature DB >> 22531396

Outcome analysis of 541 women undergoing breast conservation therapy.

David A Kelly1, Benjamin C Wood, Gregory M Knoll, Shu C Chang, John C Crantford, Gaurav D Bharti, Edward A Levine, James T Thompson.   

Abstract

Breast conservation therapy (BCT) has evolved as a favorable approach to the management of early-stage breast cancer. Shortcomings of BCT include the potential need for re-excision in the event of positive tumor margins as well as the untoward sequelae of radiation therapy. Both of those factors have led to a substantial proportion of patients undergoing BCT who ultimately report suboptimal aesthetic outcomes. Application of plastic surgery principles to the management of this patient subset has been shown to be beneficial from both an oncologic and cosmetic perspective.The aim of this study was to identify factors that may predict which patients would benefit most from involvement of a plastic surgeon before BCT. A retrospective analysis was performed on 762 patients undergoing lumpectomy during a 10-year study period at a single institution. Younger women and patients with tumor size approaching 2 cm were noted to have a significantly higher likelihood of oncologic outcomes that ultimately required breast reconstruction. Integration of oncoplastic techniques in the surgical management of patients undergoing BCT would likely contribute to improvement in aesthetic outcomes and overall patient satisfaction.

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Year:  2012        PMID: 22531396     DOI: 10.1097/SAP.0b013e31823b6ae3

Source DB:  PubMed          Journal:  Ann Plast Surg        ISSN: 0148-7043            Impact factor:   1.539


  3 in total

1.  Systematization of Oncoplastic Surgery: Selection of Surgical Techniques and Patient-Reported Outcome in a Cohort of 1,035 Patients.

Authors:  Mahdi Rezai; Sarah Knispel; Stephanie Kellersmann; Hildegard Lax; Rainer Kimmig; Peter Kern
Journal:  Ann Surg Oncol       Date:  2015-02-12       Impact factor: 5.344

2.  An In Vitro Approach for Investigating the Safety of Lipotransfer after Breast-Conserving Therapy.

Authors:  Theresa Promny; Chiara-Sophia Kutz; Tina Jost; Luitpold V Distel; Sheetal Kadam; Rafael Schmid; Andreas Arkudas; Raymund E Horch; Annika Kengelbach-Weigand
Journal:  J Pers Med       Date:  2022-08-05

3.  Centrifugation versus PureGraft for fatgrafting to the breast after breast-conserving therapy.

Authors:  Ondrej Mestak; Andrej Sukop; Yu-Sheng Hsueh; Martin Molitor; Jan Mestak; Jana Matejovska; Lucie Zarubova
Journal:  World J Surg Oncol       Date:  2014-06-05       Impact factor: 2.754

  3 in total

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